BI-99179
|
|
BI-99179 속성
- 끓는 점
- 603.1±55.0 °C(Predicted)
- 밀도
- 1.25±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 15.72±0.40(Predicted)
- 물리적 상태
- Solid
- 색상
- White to off-white
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
그림문자(GHS): | |||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
|
||||||||||||||||||||||||||||
예방조치문구: |
|
BI-99179 C화학적 특성, 용도, 생산
Biochem/physiol Actions
BI 99179 is a non-cytotoxic (by LDH release; 30 μM, U937) orally available, brain-penetrant, highly potent and selective fatty acid synthase (FAS, FASN) inhibitor (IC50 = 79 nM by cell-free human FAS assay) with little or no inhibitory potency toward a panel of 30 receptors & channels (<20%>10 μM). BI 99179 inhibits cellular FAS activity in vitro (IC50 = 180 nM/human H1975, 600 nM/murine hypothalamic N-42 cells) and increases hypothalamic [malonyl-CoA] in rats in vivo (2 h post 10 mg/kg or 2-24 hr post 100 mg/kg p.o.). Note: adverse effects in rats are reported at day 4 (30 mg/kg) and day 9 (3 mg/kg).BI-99179 준비 용품 및 원자재
원자재
준비 용품
BI-99179 공급 업체
글로벌( 9)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
SPIRO PHARMA | |
eric_feng1954@126.com | China | 9254 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
Guangzhou Younan Technology Co., Ltd | 020-020-82000279 18988968278 |
sales@ubiochem.com | China | 4324 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |
TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 23963 | 58 |
RD International Technology Co., Limited | 18024082417 |
market@ubiochem.com | China | 9274 | 58 |