1,3-디이소프로필 카보디아미드
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1,3-디이소프로필 카보디아미드 속성
- 녹는점
- 210-2120C (dec)
- 끓는 점
- 145-148 °C(lit.)
- 밀도
- 0.815 g/mL at 20 °C(lit.)
- 증기압
- 34.9hPa at 55.46℃
- 굴절률
- n
20/D 1.433(lit.)
- 인화점
- 93 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 에 용해됨클로로포름, 염화메틸렌, 아세토니트릴, 디옥산, 디메틸포름아미드 및 테트라히드로푸란에 용해됩니다.
- 물리적 상태
- 액체
- 색상
- 무색~황색으로 투명함
- 감도
- Moisture Sensitive
- BRN
- 878281
- 안정성
- 휘발성 물질
- InChIKey
- BDNKZNFMNDZQMI-UHFFFAOYSA-N
- LogP
- 4.11 at 20℃
- CAS 데이터베이스
- 693-13-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T+,T,F,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 10-26-36/37/38-41-42/43-37/38 | ||
안전지침서 | 26-36/37/39-45-38-28A-16-22 | ||
유엔번호(UN No.) | UN 2929 6.1/PG 1 | ||
WGK 독일 | 3 | ||
RTECS 번호 | FF2175000 | ||
F 고인화성물질 | 10-21 | ||
위험 참고 사항 | Flammable/Highly Toxic/ | ||
TSCA | Yes | ||
위험 등급 | 6.1 | ||
포장분류 | II | ||
HS 번호 | 29252000 | ||
유해 물질 데이터 | 693-13-0(Hazardous Substances Data) | ||
유해화학물질 필터링 | 2019-1-951(신규화학물질) | ||
함량 및 규제정보 | 물질구분: 유독물질; 혼합물(제품)함량정보: N,N'-메탄테트라일비스(2-프로판아민) [N,N'-Methanetetraylbis(2-propanamine); 693-13-0] 및 이를 2.5% 이상 함유한 혼합물 |
1,3-디이소프로필 카보디아미드 C화학적 특성, 용도, 생산
개요
Diisopropylcarbodiimide (DIC) is a clear liquid that can be easily dispensed by volume. It slowly reacts with moisture from the air, so for long term storage the bottle should be flushed with dry air or inert gas and sealed tightly. It is used in peptide chemistry as a coupling reagent. It is very toxic and caused contact dermatitis in a laboratory worker.화학적 성질
N,N'-Diisopropylcarbodiimide is colorless to pale yellow liquid. Insoluble in water, soluble in benzene, ethanol, ether.용도
N,N'-Diisopropylcarbodiimide is used as a reagent in synthetic organic chemistry. It serves as a chemical intermediate and as a stabilizer for Sarin (chemical weapon). It is also used in the synthesis of peptide and nucleic acid. Further, it is used as an antineoplastic and involved in the treatment of malignant melanoma and sarcomas. In addition to this, it is used in the synthesis of acid anhydride, aldehyde, ketone and isocyanate.정의
ChEBI: A carbodiimide compound having an isopropyl substituent on both nitrogen atoms.일반 설명
N,N′-Diisopropylcarbodiimide (DIC) is a carbodiimide used as a coupling reagent in the synthesis of amides, peptides, ureas, heterocycles, and unsymmetrical carbodiimides. It is also used in the polymerization reactions as an activator.색상 색인 번호
It is used in peptide chemistry as a coupling reagent. It is very toxic and causes contact dermatitis in labora- tory workers.Synthesis
Add N, N'diisopropylthiourea to the autoclave and use xylene as the solvent. The mass ratio of N, N'diisopropylthiourea to xylene solvent is 2:1. Add Sb2O4 catalyst (the amount of the catalyst is 1% of the total material), and oxygen is introduced. The temperature is increased to 115°C under a pressure of 8MPa for 4h, then lowered. Suction filtration at 15°C, decolorization, and vacuum distillation were used to obtain N, N'-Diisopropylcarbodiimide. The yield is 94.55%, and the purity is 99.55%.![N,N'-Diisopropylcarbodiimide N,N'-Diisopropylcarbodiimide](/NewsImg/2023-12-01/6383702369188986454109729.jpg)
1,3-디이소프로필 카보디아미드 준비 용품 및 원자재
원자재
준비 용품
4-(PIPERIDINE-1-CARBONYL)PHENYLBORONIC ACID
4-(2-시아노에틸아미노카르보닐)페닐붕소산
3-(2-시아노에틸아미노카르보닐)페닐붕소산
4-(3-TERT-BUTYL-1,2,4-OXADIAZOL-5-YL)PHENYLBORONIC ACID
3-TERT-BUTYL-5-(4-BROMOPHENYL)-1,2,4-OXADIAZOLE
4-(3-TERT-BUTYL-1,2,4-OXADIAZOL-5-YL)BENZALDEHYDE
2-TERT-BUTYL-1,3-DIISOPROPYLISOUREA
4,5-Imidazolidinedione, 2,2-dichloro-1,3-bis(1-methylethyl)-
BIS(N N'-DIISOPROPYLACETAMIDINATO)NICKE&
1,3-디이소프로필 카보디아미드 공급 업체
글로벌( 617)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shanghai Z&T Chemical Co., Ltd | +86-021-33561011 +8613818804961 |
Sales@ztchemical.com.cn | China | 402 | 58 |
Hangzhou Verychem Science And Technology Co.Ltd | +86-86-57188162785 13606544505 |
lucy@verychem.com | China | 1036 | 58 |
Changzhou Zechong Biopharma Co., Ltd. | +undefined18621330623 |
sales@zechongchem.com | China | 28 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615350571055 |
Sibel@weibangbio.com | China | 5341 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5828 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
Shandong Juchuang Chemical Co., LTD | +undefined15030412209 |
admin@juchuangchem.com | China | 387 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 973 | 58 |
1,3-디이소프로필 카보디아미드 관련 검색:
디사이클로헥실카르보디이미디 트리에틸아민 1,3-디이소프로필 카보디아미드
N,N-Diethylethylenediamine
Bosutinib N-oxide
Bosutinib Impurity 5
3-Quinolinecarbonitrile,4-chloro-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-
3-ACETAMIDOPHENOL
N,N-Dimethylaminobutane
Diethylaminoethanol
2-Diisopropylaminoethanol
N,N-Diisopropylethylamine
2-Aminoethyldiisopropylamine
N,N'-DI-TERT-BUTYLETHYLENEDIAMINE
Bosutinib
3,4-Dimethoxynitrobenzene
N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine
N,N-Dicyclohexylmethylamine