ChemicalBook >제품 카탈로그 >괭이-140

괭이-140

괭이-140 구조식 이미지

카스 번호:: 138614-30-9

한글명:: 괭이-140

동의어(한글):: 괭이-140

상품명:: HOE-140

동의어(영문):: CS-1399;Firazyr;HOE 140 Acetate;lcatibant Acetate;Aldeibant acetate;HOE-140 (Icatibant);HOE140; ICATIBANT;HOE 140;HOE 140 SYNTHETIC >99% SELECTIVE B2 BRAD YKIN;colitis,Bradykinin Receptor,inhibit,angiotensin,Icatibant Acetate,HOE140,ulcerative,Icatibant,HOE-140,Inhibitor,HOE 140;d-arg-l-arg-l-pro-l-hyp-gly-l-(2-thienyl)ala-l-ser-d-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-l-(2α,3β,7aβ)-octahydro-1h-indole-2-carbonyl-l-arg

CBNumber:: CB5497052

분자식:: C59H89N19O13S.C2H4O2

포뮬러 무게:: 1364.59

MOL 파일:: 138614-30-9.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 123

괭이-140 속성

저장 조건: -20°C

용해도: DMSO:65.0(Max Conc. mg/mL);47.63(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.18(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);7.33(Max Conc. mM)

물리적 상태: 결정성 고체

색상: White to off-white

안전

WGK 독일	3

괭이-140 C화학적 특성, 용도, 생산

개요

Although it is a rare disease, HAE is an autosomal dominant disorder that can be potentially life-threatening when swelling manifests itself within the upper airways. Antagonism of the constitutively expressed B2 receptor, therefore, would not only be beneficial in the treatment of HAE but also find application in inflammatory, allergic, and hyperalgesic disorders.Designed to possess enhanced metabolic stability with the inclusion of five non-proteinogenic amino acids, icatibant is a competitive and selective B2 receptor antagonist (devoid of activity against the inducible B1 receptor) with a K_i of 2.2±0.7 nM, and it is the first downstream targeting agent to receive regulatory approval. It joins purified C1 esterase inhibitor, danazol (an attenuated androgen), and tranexamic acid (an antifibrinolytic agent) as acute and prophylactic treatments for HAE.

용도

Antagonist (bradykinin).

정의

ChEBI: An acetate salt obtained by combining icatibant with acetic acid. Used for the treatment of acute attacks of hereditary angioedema in adult patients.

괭이-140 준비 용품 및 원자재

원자재

준비 용품

괭이-140 공급 업체

글로벌( 123)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Dorne Chemical Technology co. LTD	+86-86-13583358881 +8618560316533	Ethan@dornechem.com	China	3146	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	10978	58
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1090	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	616	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29897	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39916	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177; +8617531190177	peter@yan-xi.com	China	6011	58

괭이-140 관련 검색:

Exenatide acetate Octreotide acetate Isoamyl acetate Vinyl acetate Indole-3-acetic acid Ethylenediaminetetraacetic acid Atosiban Secretin Acetate Thymosin beta 4 Gonadorelin acetate Calcitonin salmon HOE 140 HOE-140 H-GLY-PRO-ARG-OH ACETATE SALT H-LEU-ARG-OH 1-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-amine N-BENZYL-1-(1-PYRROLIDINYL)-2-PROPANAMINE