부니트로롤

부니트로롤
부니트로롤 구조식 이미지
카스 번호:
34915-68-9
한글명:
부니트로롤
동의어(한글):
부니트로롤
상품명:
Bunitrolol
동의어(영문):
Bunitrolol;dl-Bunitolol;2-nitrilo-n-tert-butylphenoxypropanolamine;1-tert-Butylamino-3-(2-cyanophenoxy)-2-propanol;3-(tert-butylamino)-1-(m-cyanophenoxy)-2-propano;1-tert-Butylamino-3-(2-nitrilophenoxy)-2-propanol;o-(3-(tert-butylamino)-2-hydroxypropoxy)-benzonitril;o-[3-(tert-Butylamino)-2-hydroxypropoxy]benzonitrile;2-(3-(tert-ButylaMino)-2-hydroxypropoxy)benzonitrile;1-(2-Cyanophenoxy)-2-hydroxy-3-tert-butylaminopropane
CBNumber:
CB5947087
분자식:
C14H20N2O2
포뮬러 무게:
248.32
MOL 파일:
34915-68-9.mol

부니트로롤 속성

녹는점
163-165 °C
끓는 점
414.2±35.0 °C(Predicted)
밀도
1.09±0.1 g/cm3(Predicted)
저장 조건
Refrigerator, under inert atmosphere
용해도
클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨, 초음파 처리)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
13.76±0.20(Predicted)
색상
무색~담황색 점착성 오일

안전

부니트로롤 C화학적 특성, 용도, 생산

Originator

St resson,Boehringer Ingelheim,Boehringer Ingelheim,1976

Manufacturing Process

Epichlorohydrin and 2-cyanophenol are first reacted to give 1-(2- cyanophenoxy)-2,3-epoxypropane.
15 g (0.085 mol) of 1-(2-cyanophenoxy)-2,3-epoxy propane were dissolved in 100 ml of ethanol and 18.6 g (0.255 mol) of t-butylamine were added thereto. After standing for 1 hour at room temperature, the solution was heated at 60°-70°C for 2 hours after which the volatile constituents were distilled off in vacuo. The residue was digested with dilute HCl, and the insoluble constituents were vacuum filtered off. Then the filtrate was made alkaline with NaOH and the precipitating base was taken up in ether. After the ether solution had been dried over MgSO4, the ether was distilled off and the residue was dissolved in ethanol and by addition of ethereal HCl, the hydrochloride was precipitated there from in crystalline form which after recrystallization from ethanol with an addition of ether gave9.8 g of 1-(2- cyanophenoxy)-2-hydroxy-3-t-butylamino propane hydrochloride having a melting point of 163°-165°C.

Therapeutic Function

Antianginal

부니트로롤 준비 용품 및 원자재

원자재

준비 용품


부니트로롤 공급 업체

글로벌( 33)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Alfa Chemistry

Info@alfa-chemistry.com United States 24072 58
Aromsyn Co., Ltd.
+86-0571-85585865 +8613336024896
CB@aromsyn.com China 19183 58
Guangzhou CATO Research Chemicals Inc.
+86-020-81960175-617 +8615602392859
Intermediate@cato-chem.com China 8046 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
Shanghai Boc Chemical Co.,Ltd 021-34975603-808 18721111801
sales@bocpharma.com China 997 64
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2123 70
Aikon International Limited 025-66113011 18112977050
cb6@aikonchem.com China 15494 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57423 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8617 58

Copyright 2019 © ChemicalBook. All rights reserved