바트록소스타틴 C화학적 특성, 용도, 생산
효소 저해제
This cysteine-rich, 71-residue disintegrin (MW = 7602.46 g/mol; CAS 130357-67-4), from the snake Bothrops atrox (Barba amarilla) contains an RGD loop that facilitates high-affinity binding to integrins in a manner that inhibits ADP-induced platelet aggregation (IC50 = 133 nM), about 1000- times higher than that of Arg-Gly-Asp-Ser tetrapeptide. In addition, batroxostatin was about 400-times more potent than Arg-Gly-Asp-Ser at inhibiting melanoma cell adhesion to fibronectin. When covalently attached to plastic culture dishes, batroxostatin promoted adhesion of melanoma cells.
바트록소스타틴 준비 용품 및 원자재
원자재
준비 용품
