아잘란스타트

아잘란스타트
아잘란스타트 구조식 이미지
카스 번호:
143393-27-5
한글명:
아잘란스타트
동의어(한글):
아잘란스타트
상품명:
azalanstat
동의어(영문):
Rs-21607;Rs 21607;azalanstat;Unii-2nl79ni1ws;Azalanstat [inn];Azalanstat mesylate;Benzenamine, 4-[[[(2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl]thio]-;Benzenamine, 4-(((2-(2-(4-chlorophenyl)ethyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methyl)thio)-, (2S-cis)-
CBNumber:
CB61377064
분자식:
C22H24ClN3O2S
포뮬러 무게:
429.96
MOL 파일:
143393-27-5.mol

아잘란스타트 속성

녹는점
151 °C
끓는 점
647.7±40.0 °C(Predicted)
밀도
1.31±0.1 g/cm3(Predicted)
산도 계수 (pKa)
6.88±0.12(Predicted)

안전

아잘란스타트 C화학적 특성, 용도, 생산

용도

Hypolipidemic.

효소 저해제

This imidazole-containing agent (FW = 429.96 g/mol), also known as RS- 21607, inhibits both inducible heme oxygenase-1 and constitutive heme oxygenase-2 (rat IC50 = 5.3 and 24.5 μM, respectively). The m aminophenyl analogue is a slightly stronger inhibitor of heme oxygenase-1 (IC50 = 1 μM). Azalanstat is a stronger inhibitor of lanosterol 14a demethylase (rat and human Ki = 2.5 and 0.79 nM, respectively). The other three stereoisomers are weaker inhibitors of the demethylase. Target(s): aromatase, or CYP19; cholestanetriol 26-monooxygenase, or cholesterol 27-monooxygenase; cholesterol 7a-monooxygenase (CYP7)3,4; cholesterol monooxygenase, side-chain cleaving; CYP1A1; CYP1A2; CYP2C9; CYP2D6; heme oxygenase; progesterone 6b-monooxygenase, or CYP3A; progesterone 16a monooxygenase; steroid 11b monooxygenase; steroid 17a monooxygenase, or steroid 17a/20-lyase; steroid 21 monooxygenase; sterol 14-demethylase, or CYP5; lanosterol 14a-demethylase.

아잘란스타트 준비 용품 및 원자재

원자재

준비 용품


아잘란스타트 공급 업체

글로벌( 4)공급 업체
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TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
TargetMol Chemicals Inc. 4008200310
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Suzhou Meishi Biotechnology Co., Ltd. 1173954148q
meishipharma@126.com China 20035 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
sales@chemhifuture.com China 4659 58

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