모노클로로아세트알데히드
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모노클로로아세트알데히드 속성
- 녹는점
- -28--23°C
- 끓는 점
- 80-100 °C(lit.)
- 밀도
- 1.236 g/mL at 25 °C
- 증기압
- 100 at 20 °C (NIOSH, 1997)
- 굴절률
- n
20/D 1.407
- 인화점
- 128 °F
- 용해도
- 에테르(Weast, 1986), 아세톤 및 메탄올(Hawley, 1981)에 용해됩니다.
- 물리적 상태
- 무색의 액체
- 수용성
- 아세톤, 메탄올에 용해됩니다. 물에 완전히 섞임.
- 감도
- Air Sensitive
- Merck
- 2109
- BRN
- 1071226
- 노출 한도
- Ceiling 3 mg/m3 (1 ppm) (ACGIH); IDLH.
- LogP
- 0.62 at 25℃ and pH5.8
- CAS 데이터베이스
- 107-20-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T+,N | ||
---|---|---|---|
위험 카페고리 넘버 | 24/25-26-34-40-50-35 | ||
안전지침서 | 26-28-36/37/39-45-61 | ||
유엔번호(UN No.) | UN 2232 6.1/PG 1 | ||
OEL | Ceiling: 1 ppm (3 mg/m3) | ||
WGK 독일 | - | ||
RTECS 번호 | AB2450000 | ||
TSCA | Yes | ||
위험 등급 | 6.1(a) | ||
포장분류 | I | ||
HS 번호 | 29130000 | ||
유해 물질 데이터 | 107-20-0(Hazardous Substances Data) | ||
독성 | Acute oral LD50 for rats 75 mg/kg, mice 69 mg/kg (quoted, RTECS, 1985). | ||
IDLA | 45 ppm | ||
기존화학 물질 | KE-05490 |
모노클로로아세트알데히드 C화학적 특성, 용도, 생산
화학적 성질
Chloroacetaldehyde is a combustible, colorless liquid with a very sharp, irritating odor.물리적 성질
Clear, colorless liquid with an irritating, acrid odor용도
Chloroacetaldehyde is used in the productionof 2-aminothiazole.정의
ChEBI: Chloroacetaldehyde is acetaldehyde substituted at C-2 by chlorine. It derives from an acetaldehyde.일반 설명
A clear colorless liquid with a pungent odor. Flash point about 190°F. Corrosive to skin and mucous membranes. Chloroacetaldehyde is very toxic by inhalation.공기와 물의 반응
Soluble in water. Forms an insoluble hemihydrate at greater than 50% concentration.반응 프로필
Chloroacetaldehyde polymerizes on standing. At greater than 50% concentration in water, Chloroacetaldehyde forms an insoluble hemihydrate. Sensitive to heat. Reacts with oxidizing agents. Incompatible with acids and water . Burns to give poisonous and irritating gases.위험도
Corrosive to skin and mucous membranes. TLV: ceiling 1 ppm.건강위험
Chloroacetaldehyde is a highly toxic andcorrosive compound that can injure the eyes,skin, and respiratory system. Exposure toits vapor at high concentrations can producesevere irritation and impair vision. At lowconcentrations, the vapor can cause irritationand sore eyelids. Brief contact with 40%aqueous solution can result in skin burn anddestruction of tissues. A 0.5% dilute solutioncan still be irritating on skin.Inhalation of its vapor at the 5-ppm levelcan irritate the eyes, nose, and throat. Ingestionmay result in pulmonary edema. Swallowinga concentrated solution may be fatal.The acute toxicity data are as follows:
LD50 value, intraperitoneal (rats): 2 mg/kg
LD50 value, oral (rats): 23 mg/kg
LD50 value, skin (rabbits): 67 mg/kg
This compound is a mutagen, testing positivein the Ames test.
화재위험
Combustible; flash point (closed cup) 87.8°C (190°F); flash point of 50% aqueous solution 53°C (128°F) (at this concentration it may form insoluble hemihydrate); it forms an explosive mixture with air. Reactions with strong acids and oxidizers are exothermic.Safety Profile
Suspected carcinogen. Poison by ingestion, skin contact, and intraperitoneal routes. Mutation data reported. Combustible when exposed to heat or flame. Reacts with oxidizing materials. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of Cl-. See also ALDEHYDES and CHLORIDES.잠재적 노출
Chloroacetaldehyde is used as a fungicide; as an intermediate in 2-aminothiazole manufacture; and in bark removal from tree trunks.Carcinogenicity
Chloroacetaldehyde has been reported to be an inhibitor of DNA synthesis and to form DNA adducts; it is mutagenic in Salmonella typhimurium and in Chinese hamster cells.Limited in vivo genotoxicity studies with chloroacetaldehyde were negative.
환경귀착
Chemical/Physical. Polymerizes on standing (Windholz et al., 1983).운송 방법
UN22322-Chloroethanal, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, Inhalation Hazard Zone B.비 호환성
Heat and water sensitive; concentrations of .50% form insoluble hemihydrate material on contact with water. Reacts with oxidizers, acids. On heating,chloroacetaldehyde releases chlorine fumes. Polymerizable upon standing폐기물 처리
Incineration, preferably after mixing with another combustible fuel; care must be exercised to assure complete combustion to prevent the formation of phosgene; an acid scrubber is necessary to remove the halo acids produced.모노클로로아세트알데히드 준비 용품 및 원자재
원자재
준비 용품
5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-D]pyrimidine ,97%
티디아주론
2-아미노티아졸
2-아미노-2-티아졸린염산염
2-Isobutylthiazole
2-Oxo-(2H)-furo(2,3-h)-1-benzopyran
5-아미노-1,2,3-티아디아졸
아미노아세트알데하이드디에틸아세탈
6-Bromoimidazo[1,2-a]pyridine
6,8-디브로모이미다조[1,2-A]피라진
Imidazo[1,2-b]pyridazine
베타-클로로락틱산
이미다조[1,2-a]피리딘,6-플루오로-(9CI)
4-티아졸린-2-온
메틸2-메틸-3-푸로에이트
4-(2-클로로에틸)모르폴린
2-티아졸메탄아민
메틸이미다조[1,2-A]피리딘-6-카르복실레이트