4'-히드록시아세토페논
|
|
4'-히드록시아세토페논 속성
- 녹는점
- 132-135 °C(lit.)
- 끓는 점
- 147-148 °C3 mm Hg(lit.)
- 밀도
- 1.109
- 증기압
- 0.002Pa at 20℃
- 굴절률
- 1.5577 (estimate)
- 인화점
- 166 °C
- 저장 조건
- Store below +30°C.
- 용해도
- 메탄올: 0.1 g/mL, 투명
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 8.05(at 25℃)
- 색상
- 거의 흰색~베이지색
- Specific Gravity
- 1.109
- 냄새
- 디프로필렌 글리콜 중 10.00%. 순하고 달콤한 산사나무 발삼 미모사
- ?? ??
- 꽃향기
- 수용성
- 10g/L(22℃)
- JECFA Number
- 2040
- BRN
- 774355
- InChIKey
- TXFPEBPIARQUIG-UHFFFAOYSA-N
- LogP
- 1.35 at 25℃
- CAS 데이터베이스
- 99-93-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-22 | ||
안전지침서 | 26-36/37-37/39-24/25-22-36 | ||
WGK 독일 | 3 | ||
RTECS 번호 | PC4959775 | ||
위험 참고 사항 | Irritant | ||
TSCA | Yes | ||
HS 번호 | 29145000 | ||
기존화학 물질 | 2015-3-6897 |
4'-히드록시아세토페논 C화학적 특성, 용도, 생산
존재
이 원료는 주로 여러해살이 풀인 캄프리, 상수리나무, 밀의 싹 등에서 추출하는 유기화합물.용도
제약 중간체.화학적 성질
almost white to beige crystalline powder출처
Reported found in cloudberry, coffee, cranberry, mango, sherry, and wort.용도
4?-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.제조 방법
Preparation by Fries rearrangement of phenyl acetate with Lewis acidsaluminium chloride
in nitrobenzene at 20–25° or at 50–60°
in chlorobenzene between 45° and 65°, sealed tube and subjected to high power microwave irradiation for 2 min only (36%)
in nitroethane at 60° (44%)
in carbon disulfide at 45° (40%)
in petroleum ether at 50° (20%)
but between 130° and 175° (40–60%)
aluminium chloride–sodium chloride mixture at 240–250° (10%)
boron trifluoride at 90° (56%)
scandium tris(trifluoromethanesulfonate), in nitromethane, at 50° (39%)
titanium tetrachloride at 90–100° (34%)
ferric chloride at 65° (25%)
zinc chloride at 125° (8%)
hydrofluoric acid, between 20° and 100° (94%)
polyphosphoric acid, between 20° and 100° (69%) (50–53%)(44%)
Nafion-XR 500, sulfonic acid type at 100°
ZSM-5, in sulfolane, at 180° (28%)
H-ZSM-5 at 400° or at 210° (6%)
H-Nu-2 at 170° (15%)
HY (Si/Al = 3) or fluorided alumina (Al2O3-F; 3 % wt. F), at 400°.
정의
ChEBI: A monohydroxyacetophenone carrying a hydroxy substituent at position 4'.주요 응용
4'-Hydroxyacetophenone has been suggested for use in perfume compositions as a modifier for the more conventional derivatives of Acetophenonc, etc. mainly in heavy-floral or woodyfloral fragrances where power and low cost arc requested.일반 설명
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsPurification Methods
Crystallise it from diethyl ether, aqueous EtOH or *benzene/pet ether. [Beilstein 8 H 87, 8 IV 339.]4'-히드록시아세토페논 준비 용품 및 원자재
원자재
준비 용품
4-퀴녹살린-2-일페놀
아세트아미노펜
4-Vinylphenol
아테놀올
1-(3-클로로메틸-4-하이드록시-페닐)-에타논
4-Benzyloxy-3-nitroacetophenone
2-(4-히드록시페닐)에탄올
1-(4-아세틸옥시)-3-((아세틸옥시)메틸)페닐)-2-브로모에타논
HPG
4-아세틸옥시-3-아세틸옥시메틸-(N-벤질-N-tert부틸아미노)아세토페논염산염
4-에텐일페놀 아세트산
1,1,1-트리스(4-하이드록시페닐)에탄
Micafungin측쇄메틸에스테르
3',5'-DICHLORO-4'-HYDROXYACETOPHENONE
4-HYDROXYBENZOYLACETICACID메틸에스테르
4′-피퍼리디노아세토페논
2-(4-하이드록시페닐)프로피온산
4'-히드록시아세토페논 공급 업체
글로벌( 974)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
.GZ HONESTCHEM CO.,LTD | +86-15013270415 |
honestchemical@foxmail.com | China | 246 | 58 |
Shandong Believe Chemical PTE.LTD | +86-18553607090 +8618553607090 |
1093908296@qq.com | China | 1672 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 |
admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 12272 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3878 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12495 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5895 | 58 |
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 |
admin@firsky-cn.com | China | 436 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |