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샤68

샤68 구조식 이미지

카스 번호:: 847553-89-3

한글명:: 샤68

동의어(한글):: 샤68

상품명:: SHA 68

동의어(영문):: SHA 68;N-(4-fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-1H-oxazolo[3,4-a]pyrazine-7(3H)-carboxamide;N-(4-Fluorobenzyl)-3-oxo-1,1-diphenyltetrahydro-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide;N-[(4-Fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-3H-oxazolo[3,4-a]pyrazine-7(1H)-carboxamide;N-[(4-fluorophenyl)methyl]-3-oxo-1,1-diphenyl-hexahydro-1H-[1,3]oxazolo[3,4-a]pyrazine-7-carboxamide;3H-Oxazolo[3,4-a]pyrazine-7(1H)-carboxamide, N-[(4-fluorophenyl)methyl]tetrahydro-3-oxo-1,1-diphenyl-

CBNumber:: CB73037532

분자식:: C26H24FN3O3

포뮬러 무게:: 445.49

MOL 파일:: 847553-89-3.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 59

샤68 속성

끓는 점: 727.8±60.0 °C(Predicted)

밀도: 1.35±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMF: 16 mg/ml; DMSO: 14 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml

물리적 상태: 결정성 고체

산도 계수 (pKa): 13.32±0.40(Predicted)

색상: White to off-white

안전

샤68 C화학적 특성, 용도, 생산

개요

SHA-68 is an antagonist of the neuropeptide S receptor (NPSR; IC₅₀s = 22 and 23.8 nM for the NPSR Asn¹⁰⁷ and NPSR Ile¹⁰⁷ isoforms, respectively). It is selective for NPSR over a panel of 14 G protein-coupled receptors exhibiting no activity at a concentration of 10 μM. SHA-68 (50 mg/kg) reduces NPS-induced horizontal activity and vertical rearing and climbing in mice. SHA-68 also reduces conditioned reinstatement of cocaine seeking in rats.

용도

SHA 68 is a selective neuropeptide S antagonist.

샤68 준비 용품 및 원자재

원자재

준비 용품

샤68 공급 업체

글로벌( 59)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32951	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32077	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30241	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58

샤68 관련 검색:

SH-4-54 SH5-07