XAP044
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XAP044 속성
- 끓는 점
- 485.7±45.0 °C(Predicted)
- 밀도
- 1.853±0.06 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- ≤10mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
- 물리적 상태
- 결정질 고체
- 산도 계수 (pKa)
- 6.70±0.20(Predicted)
안전
XAP044 C화학적 특성, 용도, 생산
개요
XAP044 is an antagonist of the metabotropic glutamate (mGlu) receptor 7 (mGluR7), inhibiting lateral amygdala long term potentiation in brain slices from wild-type mice with an IC50 value of 88 nM. This effect is absent in mGluR7-deficient mice. XAP044 demonstrates good brain penetrance, producing wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral tests.용도
XAP 044 is a potent mGlu7 antagonist used in the treatment of anxiety and depression in mice (1,2). Applications towards stress, autism and drug abuse are also potential uses.XAP044 준비 용품 및 원자재
원자재
준비 용품
XAP044 공급 업체
글로벌( 40)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9708 | 58 |
| Block Chemical Technology (Shanghai) Co., LTD | 021-20432219 13918097649 |
li_jinfei@acblock-lab.com | China | 9562 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 |
15151849396@163.com | China | 997 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44843 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24017 | 58 |