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DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE

DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE 구조식 이미지

카스 번호:: 632-93-9

상품명:: DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE

동의어(영문):: Dicarbethoxydihydrocollidine;1,4-Dihydro-3,5-dicarbethoxycollidine;3,5-dicarbethoxy-1,4-dihydrocollidine;3,5-diethoxycarbonyl-1,4-dihydrocollidine;3,5-dicarbethoxy-1,4-dihydrocollidine, DDC;3,5-Bis(ethoxycarbonyl)-1,4-dihydrocollidine;3,5-DIETHOXYCARBONYL-1,4-DIHYDRO-2,4,6-COLLIDINE;Diethyl 1,4-dihydro-s-collidine-3,5-dicarboxylate;3,5-DICARBETHOXY-1,4-DIHYDRO-2,4,6-TRIMETHYLPYRIDINE;3,5-Diethoxycarbonyl-1,4-dihydro-2,4,6-collidine >

CBNumber:: CB7373477

분자식:: C14H21NO4

포뮬러 무게:: 267.32

MOL 파일:: 632-93-9.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 91

DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE 속성

녹는점: 130-132 °C(lit.)

끓는 점: 410.51°C (rough estimate)

밀도: 1.1116 (rough estimate)

굴절률: 1.5280 (estimate)

저장 조건: Keep in dark place,Sealed in dry,Room Temperature

용해도: DMF: 30 mg/ml; DMF:PBS (pH 7.2); (1:7): 0.125 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml

물리적 상태: powder to crystal

산도 계수 (pKa): 3.53±0.70(Predicted)

색상: White to Orange to Green

CAS 데이터베이스: 632-93-9(CAS DataBase Reference)

EPA: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, diethyl ester (632-93-9)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xi
위험 카페고리 넘버	36/37/38
안전지침서	26-37/39
WGK 독일	3
RTECS 번호	US7979375
HS 번호	2933.39.9200

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P271	옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352	피부에 묻으면 다량의 물로 씻으시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

NFPA 704

	1
2		0

DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE C화학적 특성, 용도, 생산

개요

Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (DDC) inhibits heme production by inhibiting ferrochelatase, the enzyme that catalyzes the addition of Fe²⁺ to protoporphyrin IX to create heme B. Chronic DDC administration induces Mallory-Denk body formation, a feature of alcoholic and non-alcoholic hepatitis, and reduces IL-12A methylation in mouse liver.

화학적 성질

almost white crystalline powder

용도

Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate was used to induce Mallory-Denk body formation in mice in vivo.

정의

ChEBI: A dihydropyridine that is 2,4,6-trimethyl-1,4-dihydropyridine substituted by ethoxycarbonyl groups at positions 3 and 5.

Purification Methods

Crystallise the ester from hot EtOH/water mixture. [Beilstein 22 H 147, 22 I 529, 22 II 100, 22 III/IV 1594.]

DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE 준비 용품 및 원자재

원자재

준비 용품

DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE 공급 업체

글로벌( 91)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34553	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	7724	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32343	55

DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE 관련 검색:

2,4,6-콜리딘 3,5-피리딘디카르복시산 Diethyl pyridine-3,5-dicarboxylate DIETHYL 1,4-DIHYDRO-2,4,6-TRIMETHYL-3,5-PYRIDINEDICARBOXYLATE Nimodipine 3,5-PYRIDINEDICARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-4-(3,4,5-TRIMETHOXYPHENYL)-, DIETHYL ESTER 2,6-DIMETHYL-1,4-DIHYDRO-PYRIDINE-3,4,5-TRICARBOXYLIC ACID 3,5-DIETHYL ESTER DIETHYL 1,4-DIHYDRO-2,6-DIMETHYL-4-(4-F& DIETHYL 4-ETHYL-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE Diethyl2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate 2,6-Dimethyl-4-(2-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester AURORA 3177 LABOTEST-BB LT00261244 AURORA 3480 diethyl 2,6-dimethyl-4-thiophen-2-yl-1,4-dihydropyridine-3,5-dicarboxylate DIETHYL 1,4-DIHYDRO-2,6-DIMETHYL-1,4-DIPHENYL-3,5-PYRIDINEDICARBOXYLATE AURORA 4028 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(1,3-BENZODIOXOL-5-YL)-1,4-DIHYDRO-2,6-DIMETHYL-, DIETHYL ESTER