4-Hydroxycinnamic acid

4-Hydroxycinnamic acid 구조식 이미지
카스 번호:
7400-08-0
상품명:
4-Hydroxycinnamic acid
동의어(영문):
4-Hydroxycinnamic acid;4-Hydroxycinnamic acid;P-HYDROXYCINNAMIC ACID;TRANS-4-COUMARIC ACID;TRANS-P-COUMARIC ACID;PHCA;P-CUMARIC ACID;TRANS-P-CUMARIC ACID;4-hydroxylcinnamic acid;3-(4-HYDROXYPHENYL)ACRYLIC ACID
CBNumber:
CB9164396
분자식:
C9H8O3
포뮬러 무게:
164.16
MOL 파일:
7400-08-0.mol

4-Hydroxycinnamic acid 속성

녹는점
214 °C (dec.)(lit.)
끓는 점
251.61°C (rough estimate)
밀도
1.2132 (rough estimate)
굴절률
1.5380 (estimate)
저장 조건
Store below +30°C.
용해도
아세톤(약간), 클로로포름(약간), 메탄올(약간)에 용해됨
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
4.65±0.10(Predicted)
색상
흰색에서 황백색까지
안정성
감광성
InChI
InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)
InChIKey
NGSWKAQJJWESNS-UHFFFAOYSA-N
SMILES
C(O)(=O)C=CC1=CC=C(O)C=C1
LogP
1.790
CAS 데이터베이스
7400-08-0(CAS DataBase Reference)
NIST
2-Propenoic acid, 3-(4-hydroxyphenyl)-(7400-08-0)
EPA
p-Hydroxycinnamic acid (7400-08-0)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-36-36/37/39-22
WGK 독일 2
RTECS 번호 GD9095000
HS 번호 2918 29 00
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352 피부에 묻으면 다량의 물로 씻으시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
2 0

4-Hydroxycinnamic acid C화학적 특성, 용도, 생산

화학적 성질

Light yellow to beige crystalline powder with aroma, soluble in methanol, ethanol, DMSO and other organic solvents, derived from synthesis.

용도

4-Hydroxycinnamic acid is the hydroxy derivative of Cinnamic Acid with antioxidant properties. It is a is a major component of lignocellulose. Studies suggest that 4-Hydroxycinnamic acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines. A recent study reports that 4-Hydroxycinnamic acid may act as a chemical castrator in bees by altering the epression of genes required for ovary development. This compound is common in pollen a major constituent of the worker bee diet, but it is not found in queen bees'royal jelly.

주요 응용

p-Hydroxycinnamic acid is mainly used as an intermediate in the pharmaceutical and perfume industries. It can react with dimethyl sulfate to produce p-anisaldehyde, react with acetaldehyde to produce p-hydroxycinnamaldehyde, and further oxidize it to produce cinnamic acid. This product can be directly oxidized to produce 4-Hydroxybenzoic acid and reduction to produce 4-Hydroxybenzyl alcohol.

정의

ChEBI: 4-coumaric acid is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate.

위험도

Moderately toxic.

Safety Profile

Moderarely toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See also COUMARIN

4-Hydroxycinnamic acid 준비 용품 및 원자재

원자재

준비 용품


4-Hydroxycinnamic acid 공급 업체

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