2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온

2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온
2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온 구조식 이미지
카스 번호:
265312-55-8
한글명:
2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온
동의어(한글):
2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온
상품명:
2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE
동의어(영문):
RYUVIDINE;Cdk4 Inhibitor III;2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione;2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE;2-methyl-5-[(4-methylphenyl)amino]benzothiazole-4,7-dione;4,7-Benzothiazoledione, 2-methyl-5-[(4-methylphenyl)amino]-
CBNumber:
CB92453429
분자식:
C15H12N2O2S
포뮬러 무게:
284.33
MOL 파일:
265312-55-8.mol
MSDS 파일:
SDS

2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온 속성

끓는 점
463.8±45.0 °C(Predicted)
밀도
1.416±0.06 g/cm3(Predicted)
저장 조건
Store at +4°C
용해도
Soluble to 20 mM in DMSO and to 5 mM in ethanol
물리적 상태
흑자색 고체
산도 계수 (pKa)
-1.63±0.20(Predicted)
색상
Brown to black

안전

2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온 C화학적 특성, 용도, 생산

용도

Ryuvidine is an antifungal agent used against pathogenic fungi.

일반 설명

A cell-permeable dioxobenzothiazole compound that acts a selective Cdk4 inhibitor (IC50 = 6.0 μM for Cdk4/D1 and >200 μM for Cdk2/A). Exhibit better cytotoxic potential against cancer cells (IC50 = 0.61, 1.08, 0.30, and 1.21 μg/ml against A 549, Col 1, HL-60, and HepG2 tumor cells, respectively) than Cisplatin (Cat. No. 232120).

생물학적 활성

Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 6.0 μ M at cdk4/cyclin D1) that displays > 33-fold selectivity over cdk2 (IC 50 > 200 μ M at cdk2/cyclin A). Cytotoxic against a range of human cancer cells (IC 50 values are 0.30, 0.61, 1.08 and 1.21 μ g/mL for HL-60, A549, Col 1 and HepG2 cells respectively).

2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온 준비 용품 및 원자재

원자재

준비 용품


2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온 공급 업체

글로벌( 44)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Shenzhen Nexconn Pharmatechs Ltd
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TargetMol Chemicals Inc.
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Aladdin Scientific
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
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EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
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Shanghai Changyan Chem & Tech Co., Ltd. 021-021-20242659 18930833303
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DC Chemicals 021-58447131 13564518121
sales@dcchemicals.com China 9412 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58

2-메틸-5-[(4-메틸페닐)아미노]-4,7-벤조티아졸레디온 관련 검색:

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