Corosolic acid

Corosolic acid 구조식 이미지
카스 번호:
4547-24-4
상품명:
Corosolic acid
동의어(영문):
Glucosol;Corosolic;Corsolicacid;Corosolicaci;Colosic acid;Colosolic acid;COROSOLIC ACID;Aorosolic Acid;Barnabas extract;Corosolic acid-RM
CBNumber:
CB9466988
분자식:
C30H48O4
포뮬러 무게:
472.7
MOL 파일:
4547-24-4.mol
MSDS 파일:
SDS

Corosolic acid 속성

녹는점
243~245℃
끓는 점
573.3±50.0 °C(Predicted)
밀도
1.14±0.1 g/cm3(Predicted)
저장 조건
2-8°C
용해도
메탄올: 용해성1mg/mL, 투명, 무색
물리적 상태
Solid
산도 계수 (pKa)
4.67±0.70(Predicted)
색상
하얀색
LogP
7.113 (est)
CAS 데이터베이스
4547-24-4(CAS DataBase Reference)

안전

WGK 독일 3
HS 번호 2918195000

Corosolic acid C화학적 특성, 용도, 생산

개요

Corosolic acid is a triterpenoid that has been found in L. speciosa leaves and has diverse biological activities, including anticancer, anti-inflammatory, antidiabetic, antihypertensive, antihyperlipidemic, and antioxidant properties. It is cytotoxic to HepG2, A549, SNU-C4, HeLa S3, and K562 cells (EC50s = 4.8, 5, 0.4, 1, and 4.3 μg/ml, respectively). Corosolic acid inhibits ear edema in mice induced by phorbol 12-myristate 13-acetate (TPA; ) with an ID50 value of 0.09 mg/ear. It reduces blood glucose levels in an insulin tolerance test in a KKAy mouse model of type 2 diabetes when administered at doses of 2 and 10 mg/kg. Corosolic acid (0.072% in the diet) reduces systolic blood pressure and serum levels of free fatty acids, the oxidative stress markers thiobarbituric acid-reactive substances (TBARS) and 8-hydroxy-2’-deoxyguanosine (8-OHdG), and the myeloperoxidase markers 3-nitrotyrosine and 3-chlorotyrosine in an SHR/NDmcr-cp (cp/cp) rat model of metabolic syndrome.

정의

ChEBI: A natural product found particularly in Rhododendron species and Eriobotrya japonica.

Corosolic acid 준비 용품 및 원자재

원자재

준비 용품


Corosolic acid 공급 업체

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Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
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Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 296 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58

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