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N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

CAS:
1207360-89-1
MF:
C24H32N6O3
MW:
452.55

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Properties

Boiling point:
571.3±50.0 °C(Predicted)
Density 
1.269
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 10 mg/ml
form 
Powder
pka
13.87±0.46(Predicted)
color 
Light yellow to yellow

Safety Information

Use

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is a potent and selective mTOR inhibitor with dose-dependent efficacy in mouse x enograft cancer models.

0 India supplier list of "N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea"

  • Product Name:GDC-0349
  • Products Intro:Brand:clearsynth | Product Number:CS-ED-01828
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  • Country/Region: Hyderabad,INDIA
  • Product Name:N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
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  • Product Name:GDC-0349 RG7603 GDC0349 RG-7603
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  • Product Name:GDC-0349
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  • Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
  • Product Name:GDC-0349
  • Products Intro:Purity: >=99% | Package: $142.9/5mg;$234.9/10mg;$528.9/25mg;$1031.9/50mg;$1857.9/100mg;Bulk package | CustNote: 99%
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  • Country/Region: UNITED STATES
  • Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
  • Product Name:GDC-0349
  • Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A892090
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  • Country/Region: CHINA
  • 5 mg$195.00
  • Product Name:GDC-0349
  • Products Intro:Brand:Caymanchem | Product Number:24058 | Purity:≥98%
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  • Country/Region: UNITED STATES
  • 10mg$270.00
    25mg$540.00
  • Product Name:(S)-1-Ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
  • Products Intro:Brand: Matrix Scientific | Product Number: 132331 | Purity: 97%
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  • Country/Region: UNITED STATES
  • Main Products: cof,mof
  • Product Name:GDC-0349,RG7603
  • Products Intro:Brand:chiralstar | Product Number:scs-695
  • Company Type: Trader
  • Country/Region: UNITED STATES

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea Related Search:

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