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8-Hydroxyquinoline

8-Hydroxyquinoline

CAS:
148-24-3
MF:
C9H7NO
MW:
145.16

Properties

Melting point:
70-73 °C(lit.)
Boiling point:
267 °C752 mm Hg(lit.)
Density 
1.0340
vapor pressure 
0.221Pa at 25℃
refractive index 
1.4500 (estimate)
Flash point:
267°C
storage temp. 
Store below +30°C.
solubility 
0.56g/l
form 
Liquid
pka
5.017(at 20℃)
color 
White to pale yellow or light beige
Water Solubility 
INSOLUBLE
Sensitive 
Light Sensitive
Merck 
14,4843
BRN 
114512
InChIKey
MCJGNVYPOGVAJF-UHFFFAOYSA-N
LogP
1.85 at 25℃

Safety Information

Symbol(GHS) 

GHS05,GHS06,GHS08,GHS09
Signal word 
Danger
Hazard statements 
H301-H317-H318-H360D-H410
Precautionary statements 
P202-P273-P280-P301+P310-P302+P352-P305+P351+P338
Hazard Codes 
Xn,Xi
Risk Statements 
22-68-36/37/38
Safety Statements 
45-36/37/39-26-36
RIDADR 
2811
WGK Germany 
3
RTECS 
VC4200000
Hazard Note 
Harmful/Irritant
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29334990
Toxicity
An LD50 value of 1,200mg/kg was reported for oral administration of 8-hydroxyquinoline to rats (straidsex unspecified; AAPCO, 1966);a value of 48 mg/kg was reported for intraperitoneal administration to mice (strain/sex unspecxed; Bernstein et al., 1963).

Use

8-Hydroxyquinoline (8HQ) is an intermediate of halogenated quinoline anti-amebic drugs, including quiniodoform, clioquinoline, diiodoquinoline and the like. These drugs exert anti-amebic effects by inhibiting intestinal commensal bacteria, and are effective against amoebic dysentery, but have no effect on extra-intestinal amoebic parasites.8HQ is a small planar molecule with a lipophilic effect and a metal chelating ability. As a result, 8HQ and its derivatives hold medicinal properties such as antineurodegenerative, anticancer, antioxidant, antimicrobial, anti-inflammatory, and antidiabetic activities.

44 India supplier list of "8-Hydroxyquinoline"

  • Product Name:8-Hydroxyquinoline, 99%
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:8-Hydroxyquinoline
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Maharashtra,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Karnataka,INDIA
  • Product Name:8-hydroxyquinoline
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA

8-Hydroxyquinoline Related Search:

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