Levobupivacaine
Levobupivacaine
- CAS:
- 27262-47-1
- MF:
- C18H28N2O
- MW:
- 288.43
Suppliers by country/region
Company Type
Properties
- Melting point:
- 136-137°C
- alpha
- D25 -80.9° (c = 5 in methanol)
- Boiling point:
- 430.65°C (rough estimate)
- Density
- 1.0238 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO:58.0(Max Conc. mg/mL);201.09(Max Conc. mM)
Ethanol:58.0(Max Conc. mg/mL);201.09(Max Conc. mM)
- pka
- 14.85±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
Safety Information
Use
Levobupivacaine is the pure “S” enantiomer of bupivacaineand in vivo and in vitro studies confirm that it does notundergo metabolic inversion to R(+) bupivacaine. The pKaof the tertiary nitrogen is 8.09, the same as bupivacaine’s pKa. Levobupivacaine is available in solution for epiduraladministration, peripheral nerve block administration, andinfiltration anesthesia. Clinical trials have shown thatlevobupivacaine and bupivacaine have similar anestheticeffects. Levobupivacaine has lower CNS and cardiotoxicitythan bupivacaine although unintended intravenousinjection when performing nerve blocks may result intoxicity. Racemic bupivacaine is metabolized extensivelywith no unchanged drug found in the urine or feces. Liverenzymes including the CYP3A4 and CYP1A2 isoforms areresponsible for N-dealkylation and 3-hydroxylation oflevobupivacaine followed by glucuronidation or sulfation.
11 India supplier list of "Levobupivacaine"
- Product Name:Levobupivacaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Levobupivacaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Levobupivacaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Levobupivacaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA
- Product Name:Levobupivacaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Levo Bupivacaine HCl (HIS)
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Levobupivacaine 97% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.038651
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:1-Butyl-N-(2,6-dimethylphenyl)-piperidine-2-carboxamide
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Levobupivacaine
- Company Type: Reagent
- Country/Region: Kolkata,INDIA
- Product Name:Levobupivacaine
- Company Type: Reagent
- Country/Region: Karnataka,INDIA