BI-D1870
BI-D1870
- CAS:
- 501437-28-1
- MF:
- C19H23F2N5O2
- MW:
- 391.42
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Company Type
Properties
- Boiling point:
- 579.3±60.0 °C(Predicted)
- Density
- 1.297
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 15 mg/ml)
- form
- Off-white solid.
- pka
- 7.68±0.36(Predicted)
- color
- Off-white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H227
- Precautionary statements
- P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235
- HS Code
- 2933599590
Use
The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. BI-D1870 is a cell permeable, ATP-competitive inhibitor of the four vertebrate isoforms of RSK, RSK1-4 (IC50s = 31, 24, 18, and 15 nM, respectively). At 100 nM, it also significantly inhibits polo-like kinase 1, Aurora B, maternal embryonic leucine zipper kinase, and mammalian STE20-like kinase 2. BI-D1870 acts at the N-terminal kinase domain, but not the C-terminal domain, of RSK.
1 India supplier list of "BI-D1870"
- Product Name:BI-D1870 >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089088
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:BI-D1870
- Products Intro:Brand:clearsynth | Product Number:CS-CW-00088
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:BI-D1870
- Products Intro:Brand:ajchemicals | Product Number:JDH-26857 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:BI-D1870
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:2-((3,5-difluoro-4-hydroxyphenyl)amino)-7,8-dihydro-5,7-dimethyl-8-(3-methylbutyl)-6(5h)-pteridinone
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:BI-D1870
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:BI-D1870 RSK Inhibitor II
- Products Intro:Purity: 99% | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:BI-D1870
- Products Intro:Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:BI-D1870
- Products Intro:Purity: >=98% | Package: $260.9/10mg;$587.9/25mg;$593.9/50mg;$1069.9/100mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:BI-D1870
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A871649
- Company Type: Reagent
- Country/Region: CHINA