Boc-N-methyl-L-leucine
Boc-N-methyl-L-leucine
- CAS:
- 53363-89-6
- MF:
- C12H23NO4
- MW:
- 245.32
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Properties
- Melting point:
- 55-60 °C
- Boiling point:
- 338.2±21.0 °C(Predicted)
- Density
- 1.053±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- pka
- 4.04±0.21(Predicted)
- form
- Solid
- color
- White to off-white
- optical activity
- [α]20/D 36±2°, c = 1% in methylene chloride
- BRN
- 2373250
- InChI
- InChI=1S/C12H23NO4/c1-8(2)7-9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t9-/m0/s1
- InChIKey
- YXJFAOXATCRIKU-VIFPVBQESA-N
- SMILES
- C(O)(=O)[C@H](CC(C)C)N(C(OC(C)(C)C)=O)C
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- WGK Germany
- 3
- HS Code
- 2924 19 00
- HazardClass
- IRRITANT
Use
Boc-N-methyl-L-leucine is the BOC (tert-butyloxycarbonyl) protected N-methylated leucine. The N-methylated amino acid is quite useful in the peptide synthesis, giving a lot of improved properties to peptide. Studies have shown that peptide containing N-methylated amino acids obtain increased proteolytic stability, increased membrane permeability, and altered conformation. The effects of N-methylated amino acids are quite important in the development of therapeutic peptide compound as well as in the assay of biological activity of some modified peptides. BOC group can be easily removed by treatment with strong acids such as trifluoroacetic acid.
1 India supplier list of "Boc-N-methyl-L-leucine"
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- Product Name:Boc-N-Me-Leu-OH
- Products Intro:Brand:sigma aldrich | Product Number:15446 | Purity:≥99.0%(sumofenantiomers,TLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Boc-N-Me-L-Leu-OH
- Products Intro:Purity: 98%|Package: 1kg;0.00;USD|10kg;0.00;USD|100kg;0.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: amino acids,Amino Acid Derivatives,Custom Peptide,Pharmaceutical Intermediates,Impurities
$0.00-0.00 / 1kg