Flurbiprofen
Flurbiprofen
- CAS:
- 5104-49-4
- MF:
- C15H13FO2
- MW:
- 244.27
Suppliers by country/region
Company Type
Properties
- Melting point:
- 110-112 °C(lit.)
- Boiling point:
- 376.2±30.0 °C(Predicted)
- Density
- 1.1795 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- methanol: soluble50mg/mL
- pka
- pKa 3.80(H2O) (Uncertain)
- form
- White solid
- color
- white to off-white
- Water Solubility
- 8mg/L(room temperature)
- Merck
- 14,4199
- InChIKey
- SYTBZMRGLBWNTM-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310+P330-P405-P501
- Hazard Codes
- T,C
- Risk Statements
- 25-23/24/25
- Safety Statements
- 36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- DU8341000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29163990
Use
Flurbiprofen (Ansaid, Ocufen, Froben), is another drug inthis class indicated for both acute and long-term managementof RA and OA but with a more complex mechanism ofaction. Unlike the other drugs in this class, it does not undergochiral inversion (i.e., the conversion of the “inactive”[R]-enantiomer to the active, [S]-enantiomer). Similar to aspirinand other salicylates, both flurbiprofen enantiomersblock COX-2 induction as well as inhibiting the nuclearfactor-κB-mediated polymorphonuclear leukocyte apoptosissignaling; therefore, both enantiomers are believed to contributeequally to its overall anti-inflammatory action.(R)-flurbiprofen is actually a strong clinical candidate forthe treatment of Alzheimer disease, because it has beenshown to reduce Aβ42 production by human cells.
88 India supplier list of "Flurbiprofen"
- Product Name:S-flurbiprofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Pune,INDIA
- Product Name:Flurbiprofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Flurbiprofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Flurbiprofen
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Flurbiprofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:FLURBIPROFEN 53% DC GRANULES
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Flurbiprofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Flurbiprofen
- Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Kerela,INDIA
- Product Name:Flurbiprofen
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:FLURBIPROFEN
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA