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Meprobamate
Meprobamate
- CAS:
- 57-53-4
- MF:
- C9H18N2O4
- MW:
- 218.25
Properties
- Melting point:
- 97-100°C
- Boiling point:
- 358.93°C (rough estimate)
- Density
- 1.2004 (rough estimate)
- refractive index
- 1.4480 (estimate)
- Flash point:
- 11 °C
- storage temp.
- 2-8°C
- solubility
- DMF: 50 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml
- pka
- 13.09±0.50(Predicted)
- Water Solubility
- 6.2g/L(25 ºC)
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xn,T,F
- Risk Statements
- 22-39/23/24/25-23/24/25-11
- Safety Statements
- 7-16-36/37-45
- RIDADR
- UN 1230 3/PG 2
- WGK Germany
- 3
- RTECS
- TZ0175000
- HS Code
- 2924110000
- Toxicity
- LD50 i.p. in mice: 800 mg/kg (Berger)
Use
Meprobamate, a bis-carbamate ester, was introduced in 1955 for the treatment of anxiety and was subsequently used as a sedative-hypnotic drug. Psychological and physical dependence can occur and abuse has been reported. Meprobamate is controlled under Schedule IV of the 1971 Convention on Psychotropic Substances. (Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV), , , 1971)
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