Mexiletine hydrochloride
Mexiletine hydrochloride
- CAS:
- 5370-01-4
- MF:
- C11H18ClNO
- MW:
- 215.72
Suppliers by country/region
Company Type
Properties
- Melting point:
- 200-203°C
- Density
- 1.12 g/cm3
- storage temp.
- 2-8°C
- solubility
- ethanol: 50 mg/mL
- form
- powder
- pka
- 9.0(at 25℃)
- color
- white
- λmax
- 272nm(MeOH)(lit.)
- Merck
- 14,6169
- Stability:
- Hygroscopic
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38-22
- Safety Statements
- 36-26
- WGK Germany
- 3
- RTECS
- KR9300000
- HS Code
- 2922190900
- Toxicity
- LD50 in male, female rats, mice, rabbits (mg/kg): 350, 400, 310, 400, 180, 160 orally; in male, female rats, mice (mg/kg): 27, 30, 43, 50 i.v. (Kast)
Use
Mexiletine hydrochloride, like class I antiarrhythmicagents, blocks the fast Na channel in cardiac cells. It isespecially effective on the Purkinje fibers in the heart. Thedrug increases the threshold of excitability of myocardialcells by reducing the rate of rise and amplitude of the actionpotential and decreases automaticity.Mexiletine hydrochloride is used for long-term oral prophylaxisof ventricular tachycardia. The drug is given in200- to 400-mg doses every 8 hours.
12 India supplier list of "Mexiletine hydrochloride "
- Product Name:Mexiletine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Mexiletine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Mexiletine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Mexiletine hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Mexiletinehydrochloride
- Products Intro:Brand:sigma aldrich | Product Number:M2727 | Purity:powder
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Mexiletine hydrochloride >98% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.071086
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Mexiletine hydrochloride
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:MEXILETINE HYDROCHLORIDE
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Mexiletine hydrochloride
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:MexiletineHydrochloride
- Products Intro:Brand:pharmaffiliates | Product Number:PA1341000
- Company Type: Trader
- Country/Region: Haryana,INDIA