Monoethyl fumarate
Monoethyl fumarate
- CAS:
- 2459-05-4
- MF:
- C6H8O4
- MW:
- 144.13
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Properties
- Melting point:
- 66-68 °C (lit.)
- Boiling point:
- 147 °C/16 mmHg (lit.)
- Density
- 1.1109
- refractive index
- 1.4500 (estimate)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- 3.45±0.10(Predicted)
- color
- Almost white to beige
- Water Solubility
- Soluble in water.
- BRN
- 1723588
- Dielectric constant
- 6.5(23.0℃)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H317-H319-H335
- Precautionary statements
- P280-P302+P352-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 1
- HazardClass
- IRRITANT
- HS Code
- 29171900
Use
Monoethyl fumarate is the Monoethyl ester form of fumarate. It is a kind of effective preservative and polymerization agent for macromolecular material. Monoethyl fumarate is capable of inhibiting the growth of bacteria, yeast and mold and prolonging the storage time of feed can. It can also be used for long-term systemic therapy in the treatment of psoriasis (a chronic hyperproliferative inflammatory skin disorder). It is the most active ingredient in the antipsoriasis drug Fumadem. The mechanism is likely to be related to its effect of improvement of keratinocyte differentiation and inhibition of keratinocyte proliferation. Monomethyl fumarate has beneficial effects on the inflamed bloodbrain barrier. It increases levels of endogenous antioxidant proteins in brain endothelial cells and reduces expression of VCAM-1 in inflamed brain endothelial cells. Transendothelial monocyte migration is limited upon MMF treatment.
3 India supplier list of "Monoethyl fumarate"
- Product Name:Quetiapine EP Impurity R Fumaric Acid Monoethyl Ester
- Products Intro:Purity: 96.56 | Package: Customize Packaging (As per customer requirement in Miligram)
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:mono-Ethylfumarate
- Products Intro:Brand:sigma aldrich | Product Number:128422 | Purity:95%
- Company Type: Trader
- Country/Region: INDIA
- Product Name:FumaricAcidMonoethylEster
- Products Intro:Brand:pharmaffiliates | Product Number:PA0648510
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Monoethyl fumarate
- Company Type: Reagent
- Country/Region: INDIA