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N-Hydroxysuccinimide

N-Hydroxysuccinimide

CAS:
6066-82-6
MF:
C4H5NO3
MW:
115.09

Properties

Melting point:
95-98 °C(lit.)
Boiling point:
215.33°C (rough estimate)
Density 
1.4769 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.4080 (estimate)
storage temp. 
Store at +2°C to +8°C.
solubility 
DMSO (Soluble), Methanol (Slightly)
pka
7.81±0.20(Predicted)
form 
Liquid or Solid
color 
Clear yellow-brown to brown
PH
5-7 (50g/l, H2O, 20℃)
Water Solubility 
SOLUBLE
Sensitive 
Hygroscopic
BRN 
113913
Stability:
Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture.
InChIKey
NQTADLQHYWFPDB-UHFFFAOYSA-N
LogP
-2.01

Safety Information

Symbol(GHS) 

GHS05
Signal word 
Danger
Hazard statements 
H315-H318
Precautionary statements 
P264-P280-P302+P352-P305+P351+P338-P332+P313-P362+P364
Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-26-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29251995

Use

N-hydroxysuccinimide (NHS) is often used to assist carbodiimide-mediated peptide coupling by forming an active ester intermediate via condensation of the surface carboxyl group and NHS. The NHS-reactive ester intermediate is susceptible to nucleophilic attack by primary amines and results in the formation of stable amide bonds between the biomaterial surface and the N-terminus of the peptide.

36 India supplier list of "N-Hydroxysuccinimide"

  • Product Name:N-Hydroxysuccinimide
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:N - Hydroxy Succinimide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:N-Hydroxysuccinimide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:N-Hydroxysuccinimide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:N-Hydroxysuccinimide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Ahmedabad,INDIA
  • Product Name:N-Hydroxy Succinimide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:N-Hydroxysuccinimide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:N-Hydroxysuccinimide, 98%
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:N-HYDROXY SUCCINIMIDE
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:N-Hydroxysuccinimide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA

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