Phenylbutazone
Phenylbutazone
- CAS:
- 50-33-9
- MF:
- C19H20N2O2
- MW:
- 308.37
Suppliers by country/region
Company Type
Properties
- Melting point:
- 106-108 °C (lit.)
- Boiling point:
- 448.76°C (rough estimate)
- Density
- 1.1591 (rough estimate)
- refractive index
- 1.6140 (estimate)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, sparingly soluble in alcohol. It dissolves in alkaline solutions.
- form
- Powder
- pka
- 4.5(at 25℃)
- color
- White to almost white
- Water Solubility
- <0.1 g/100 mL at 23.5 ºC
- Merck
- 14,7277
- BRN
- 290080
- Stability:
- Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
- InChIKey
- VYMDGNCVAMGZFE-UHFFFAOYSA-N
- LogP
- 3.160
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301-H312+H332-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P310-P302+P352+P312-P304+P340+P312-P305+P351+P338
- Hazard Codes
- Xn,T,F
- Risk Statements
- 36/37/38-20/21/22-42/43-45-36-11
- Safety Statements
- 36/37/39-26-45-22-53-36/37-16
- RIDADR
- 3249
- WGK Germany
- 3
- RTECS
- UQ8225000
- TSCA
- Yes
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29331990
- Toxicity
- LD50 oral in rabbit: 781mg/kg
Use
Phenylbutazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1949 for the treatment of rheumatic disorders. Its use was subsequently associated with serious and sometimes fatal adverse reactions, notably cases of aplastic anaemia and agranulocytosis. Many national drug regulatory authorities consider that more recently introduced drugs offer a safer alternative for most, if not all, patients requiring anti-inflammatory agents. Phenylbutazone has thus been either withdrawn at the national level or retained with rigorously restricted indications for patients unresponsive to other therapy. These restrictions also apply, in general, to combination products containing phenylbutazone.
49 India supplier list of "Phenylbutazone"
- Product Name:Phenylbutazone
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Products Intro:Brand:sigma aldrich | Product Number:79184 | Purity:analyticalstandard
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Phenylbutazone 98.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.040868
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Phenylbutazone
- Company Type: Trader
- Country/Region: INDIA