Piperazine
Piperazine
- CAS:
- 110-85-0
- MF:
- C4H10N2
- MW:
- 86.14
Suppliers by country/region
Company Type
Properties
- Melting point:
- 109-112 °C (lit.)
- Boiling point:
- 145-146 °C (lit.)
- Density
- 1,1 g/cm3
- vapor pressure
- 0.8 mm Hg ( 20 °C)
- FEMA
- 4250 | PIPERAZINE
- refractive index
- 1.4460
- Flash point:
- 65 °C
- storage temp.
- Store below +30°C.
- solubility
- H2O: 0.1 M at 20 °C, clear, colorless
- pka
- 9.83(at 23℃)
- form
- Crystalline Flakes
- color
- White to slightly yellow
- Odor
- at 0.10 % in dipropylene glycol. ammoniacal
- PH
- 11.0-12.5 (25℃, 0.1M in H2O)
- explosive limit
- 14%
- Odor Type
- ammoniacal
- Water Solubility
- 150 g/L (20 ºC)
- Sensitive
- Air Sensitive & Hygroscopic
- λmax
- λ: 260 nm Amax: 0.035
λ: 280 nm Amax: 0.010
- JECFA Number
- 1615
- Merck
- 14,7464
- BRN
- 102555
- Exposure limits
- ACGIH: TWA 0.03 ppm
- Stability:
- Stable. Hygroscopic. Light sensitive. Flammable. Incompatible with strong oxidizing agents.
- InChIKey
- GLUUGHFHXGJENI-UHFFFAOYSA-N
- LogP
- -1.24 at 20-25℃
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P305+P351+P338
- Hazard Codes
- C,Xn
- Risk Statements
- 34-42/43-52/53-62-52-63
- Safety Statements
- 22-26-36/37/39-45-61
- RIDADR
- UN 2579 8/PG 3
- WGK Germany
- 1
- RTECS
- TK7800000
- F
- 3-8-23
- Hazard Note
- Harmful/Corrosive
- TSCA
- Yes
- HS Code
- 2933 59 95
- HazardClass
- 8
- PackingGroup
- III
- Toxicity
- LD50 orally in Rabbit: 2600 mg/kg LD50 dermal Rabbit 8300 mg/kg
Use
Piperazine was first used as a treatment for gout earlier this century and its anthelminthic activity was discovered in 1949. It is also considerably cheaper than other anthelminthic drugs. In some countries where ascariasis is not endemic and where piperazine was used predominantly for the treatment of pinworm it has been withdrawn from use on the grounds that other more effective and less toxic drugs are now available (see full list). In other such countries, however, piperazine remains available in over-the-counter preparations. Clinical dosages occasionally induce transient neurological signs and concern has been expressed that in some circumstances the drug may generate small amounts of nitrosamine in the stomach. However, it is widely considered that these trace doses are unlikely to give rise to a significant carcinogenic potential. (Reference: (WHODIB) WHO Drug Information Bulletin, 1: 5, , 1983)
100 India supplier list of "Piperazine"
- Product Name:Piperazine, anhydrous, 98%
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Piperazine Anhydrous
- Products Intro:Purity: 99% | Package: 25KG;INR
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Piperazine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA