Propylene carbonate
Propylene carbonate
- CAS:
- 108-32-7
- MF:
- C4H6O3
- MW:
- 102.09
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Properties
- Melting point:
- -55 °C (lit.)
- Boiling point:
- 240 °C (lit.)
- Density
- 1.204 g/mL at 25 °C (lit.)
- vapor pressure
- 0.13 mm Hg ( 20 °C)
- refractive index
- n
20/D 1.421(lit.)
- Flash point:
- 270 °F
- storage temp.
- Store below +30°C.
- solubility
- 240g/l
- form
- Liquid
- pka
- 3.92[at 20 ℃]
- Specific Gravity
- 1.209 (20/4℃)
- color
- Clear
- Relative polarity
- 6
- Odor
- odorless
- PH
- 7.0 (200g/l, H2O, 20℃)
- explosive limit
- 1.8-14.3%(V)
- Water Solubility
- 240 g/L (20 ºC)
- λmax
- λ: 235 nm Amax: 1.00
λ: 280 nm Amax: 0.50
λ: 300 nm Amax: 0.30
λ: 350 nm Amax: 0.05
λ: 375-400 nm Amax: 0.01
- BRN
- 107913
- Dielectric constant
- 64.4(Ambient)
- Stability:
- Stable. Incompatible with strong oxidizing agents, acids, bases, reducing agents. Protect from contact with moist air or water.
- InChIKey
- RUOJZAUFBMNUDX-UHFFFAOYSA-N
- LogP
- -0.41 at 20℃
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H319
- Precautionary statements
- P264-P280-P305+P351+P338-P337+P313
- Hazard Codes
- Xi
- Risk Statements
- 36
- Safety Statements
- 26-37/39
- WGK Germany
- 1
- RTECS
- FF9650000
- F
- 3-10
- Autoignition Temperature
- 851 °F
- TSCA
- Yes
- HS Code
- 29209010
- Toxicity
- LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 20000 mg/kg
Use
Propylene carbonate is used mainly as a solvent in oral and topical pharmaceutical formulations. In topical applications, propylene carbonate has been used in combination with propylene glycol as a solvent for corticosteroids. The corticosteroid is dissolved in the solvent mixture to yield microdroplets that can then be dispersed in petrolatum.Propylene carbonate has been used as a dispensing solvent in topical preparations. Propylene carbonate has also been used in hard gelatin capsules as a nonvolatile, stabilizing, liquid carrier. For formulations with a low dosage of active drug, a uniform drug content may be obtained by dissolving the drug in propylene carbonate and then spraying this solution on to a solid carrier such as compressible sugar; the sugar may then be filled into hard gelatin capsules Propylene carbonate may additionally be used as a solvent, at room and elevated temperatures, for many cellulose-based polymers and plasticizers. Propylene carbonate is also used in cosmetics.
31 India supplier list of "Propylene carbonate "
- Product Name:Propylene Carbonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Propylene carbonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Propylene Carbonate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Propylenecarbonate
- Products Intro:Brand:sigma aldrich | Product Number:310328 | Purity:anhydrous,99.7%
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Propylene carbonate
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:PropyleneCarbonate
- Products Intro:Brand:synzeal | Product Number:206434512
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Propylene carbonate
- Company Type: Reagent
- Country/Region: INDIA