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Ruxolitinib

Ruxolitinib

CAS:
941678-49-5
MF:
C17H18N6
MW:
306.37

Properties

Melting point:
84-89°C
Density 
1.40
storage temp. 
-20°
solubility 
Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
form 
White powder.
pka
11.63±0.50(Predicted)
color 
White
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI
InChI=1/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/s3
InChIKey
HFNKQEVNSGCOJV-UJHUVDBMNA-N
SMILES
[C@@H](C1CCCC1)(N1N=CC(C2N=CN=C3NC=CC=23)=C1)CC#N |&1:0,r|

Safety Information

Symbol(GHS) 

GHS07,GHS08
Signal word 
Danger
Hazard statements 
H302-H360FD
Precautionary statements 
P202-P280
HS Code 
29335990

Use

Ruxolitinib is a small-molecule inhibitor of the tyrosine kinase (namely, jak1 and jak2) and is suitable for the treatment of intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post essential thrombocythemia myelofibrosis.

1 India supplier list of "Ruxolitinib"

  • Product Name:Ruxolitinib 98% (HPLC)
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.093341
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Ruxolitinib
  • Products Intro:Brand:synzeal | Product Number:107826629
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Ruxolitinib
  • Products Intro:Brand:clearsynth | Product Number:CS-T-61211
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Ruxolitinib
  • Products Intro:Brand:chemsworth | Product Number:207124167 | Purity:~97%
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Ruxolitinib
  • Products Intro:Brand:pharmaffiliates | Product Number:PA1882000
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Ruxolitinib
  • Products Intro:Brand:ajchemicals | Product Number:JDH-36208 | Purity:98+%
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Ruxolitinib phosphate
  • Products Intro:Purity: 0.98 | Package: 10mg, 10g, 50g, 100g, 1kg, 5kg, 10kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Ruxolitinib
  • Products Intro:Purity: 98% | Package: 1KG.5KG;25KG
  • Company Type: Trader
  • Country/Region: CHINA

    $160.00/ 1g

  • Product Name:Ruxolitinib
  • Products Intro:Purity: 99% Purity (What/sapp: +86 18145728414) | Package: 1g;160USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Ruxolitinib
  • Products Intro:Purity: 99 | CustNote: g
  • Company Type: Trader
  • Country/Region: CHINA

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