Sugammadex sodium
Sugammadex sodium
- CAS:
- 343306-79-6
- MF:
- C72H104Na8O48S8
- MW:
- 2177.97
Suppliers by country/region
Company Type
Properties
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMF: 2.5 mg/ml; DMSO: 2.5 mg/ml; DMSO:PBS (pH 7.2) (1:30): 0.03 mg/ml
- form
- A crystalline solid
- color
- White to off-white
- InChIKey
- NIOBYNJFPSIMJF-OBHNVPISNA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H302-H334
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P261-P285-P304+P341-P342+P311-P501
Use
To facilitate tracheal intubation, mechanical ventilation, and surgical access, NMB agents are frequently used as non-anesthetic adjuncts in surgical procedures. Sugammadex is able to function as a pharmacologic sink of rocuronium and vecuronium, another non-depolarizing neuromuscular blocker, without the cardiovascular adverse effects experienced with reversal agents that directly interact with the cholinergic system. The γ-cyclodextrin has been designed to enhance binding of the guest by incorporating acidic side chains to promote an electrostatic interaction with the positive nitrogen of the blocker. Starting with γ-cyclodextrin, these side chains are readily installed by first halogenating with iodine or bromine to provide a handle for nucleophilic displacement with either 3-mercaptopropionic acid in the presence of sodium hydride or with 3-mercaptopropionic acid methyl ester and cesium carbonate. The latter requires hydrolysis with sodium hydroxide to generate sugammadex sodium.
13 India supplier list of "Sugammadex sodium"
- Product Name:Sugammadex sodium
- Products Intro:Purity: Min 98% | Package: 1Kg, 5Kg, 25Kg 100Kg, MT
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Suggamadex
- Products Intro:Purity: >98% | Package: As per requirement
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Sugammadex Sodium
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA