Tamoxifen citrate
Tamoxifen citrate
- CAS:
- 54965-24-1
- MF:
- C32H37NO8
- MW:
- 563.64
Suppliers by country/region
Company Type
Properties
- Melting point:
- 140-144 °C
- storage temp.
- 2-8°C
- solubility
- methanol: soluble50mg/mL, clear, colorless
- form
- Powder
- color
- White to off-white
- Water Solubility
- slightly soluble
- Sensitive
- Light Sensitive & Hygroscopic
- Merck
- 14,9048
- BCS Class
- 1
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
- InChIKey
- FQZYTYWMLGAPFJ-OQKDUQJOSA-N
- SMILES
- C(/C1=CC=CC=C1)(\C1C=CC(OCCN(C)C)=CC=1)=C(/CC)\C1=CC=CC=C1.C(O)(C(=O)O)(CC(=O)O)CC(=O)O
Safety Information
- Symbol(GHS)
GHS07,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H302-H350-H360D-H410
- Precautionary statements
- P201-P202-P264-P273-P301+P312-P308+P313
- Hazard Codes
- T,Xi
- Risk Statements
- 45-60-61-22-64-36/37/38
- Safety Statements
- 53-36/37/39-45-36-26
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
- RTECS
- KH2387000
- HazardClass
- IRRITANT
- HS Code
- 29225090
- Toxicity
- LD50 in mice, rats (mg/kg): 200, 600 i.p.; 62.5, 62.5 i.v.; 3000-6000, 1200-2500 orally (Furr, Jordan)
Use
Tamoxifen Citrate is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. Tamoxifen is used for the treatment of invasive breast cancer in men and women, the most common type of breast cancer, following surgery and/or radiation and for preventing invasive breast cancer in women at high risk for developing it. Tamoxifen also is used for the treatment of women following surgery and radiation for a less common type of breast cancer called ductal carcinoma in situ (DCIS or Intraductal Carcinoma). Women who have had DCIS are at high risk for developing invasive breast cancer at a later date, and tamoxifen prevents development of the invasive cancer in almost half of the women during the first five years of treatment.
16 India supplier list of "Tamoxifen citrate"
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Tamoxifen citrate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:ANTI-TMX1(C-TERMINAL)antibodyproducedinrabbit
- Products Intro:Brand:sigma aldrich | Product Number:SAB1305470 | Purity:affinityisolatedantibody,bufferedaqueoussolution
- Company Type: Trader
- Country/Region: Bangalore,INDIA