2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE
![2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE price.](/CAS/GIF/265312-55-8.gif)
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- $30 - $1260
- Product name: 2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE
- CAS: 265312-55-8
- MF: C15H12N2O2S
- MW: 284.33
- EINECS:
- MDL Number:MFCD09971103
- Synonyms:2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE;RYUVIDINE;Cdk4 Inhibitor III;2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione;4,7-Benzothiazoledione, 2-methyl-5-[(4-methylphenyl)amino]-;2-methyl-5-[(4-methylphenyl)amino]benzothiazole-4,7-dione
16 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5MG
- 10mg
- 25mg
- 10
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberSYN5642
- Product descriptionRyuvidine
- Packaging50mg
- Price$757
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002654
- Product descriptionCDK4 INHIBITOR-(III) 95.00%
- Packaging5MG
- Price$495.19
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7128
- Product descriptionRyuvidine
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7128
- Product descriptionRyuvidine
- Packaging10mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7128
- Product descriptionRyuvidine
- Packaging25mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging1mg
- Price$33
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging5mg
- Price$96
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging10mg
- Price$160
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging25mg
- Price$317
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number219478
- Product descriptionCdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem
- Packaging5mg
- Price$245
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number2609
- Product descriptionRyuvidine ≥98%(HPLC)
- Packaging10
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number2609
- Product descriptionRyuvidine ≥98%(HPLC)
- Packaging50
- Price$852
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberR990010
- Product descriptionRyuvidine
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberR990010
- Product descriptionRyuvidine
- Packaging100mg
- Price$1260
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number464912
- Product descriptionRyuvidine
- Packaging1mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256545
- Product descriptionRyuvidine
- Packaging10mg
- Price$466
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5642 | Ryuvidine | 50mg | $757 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002654 | CDK4 INHIBITOR-(III) 95.00% | 5MG | $495.19 | 2021-12-16 | Buy |
| ApexBio Technology | B7128 | Ryuvidine | 5mg | $104 | 2021-12-16 | Buy |
| ApexBio Technology | B7128 | Ryuvidine | 10mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | B7128 | Ryuvidine | 25mg | $347 | 2021-12-16 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 1mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 5mg | $96 | 2024-03-01 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 10mg | $160 | 2024-03-01 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 25mg | $317 | 2024-03-01 | Buy |
| Sigma-Aldrich | 219478 | Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem | 5mg | $245 | 2024-03-01 | Buy |
| Tocris | 2609 | Ryuvidine ≥98%(HPLC) | 10 | $210 | 2021-12-16 | Buy |
| Tocris | 2609 | Ryuvidine ≥98%(HPLC) | 50 | $852 | 2021-12-16 | Buy |
| TRC | R990010 | Ryuvidine | 1mg | $30 | 2021-12-16 | Buy |
| TRC | R990010 | Ryuvidine | 100mg | $1260 | 2021-12-16 | Buy |
| Usbiological | 464912 | Ryuvidine | 1mg | $290 | 2021-12-16 | Buy |
| Usbiological | 256545 | Ryuvidine | 10mg | $466 | 2021-12-16 | Buy |
Properties
Boiling point :463.8±45.0 °C(Predicted)
Density :1.416±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble to 20 mM in DMSO and to 5 mM in ethanol
form :Black-purple solid
pka :-1.63±0.20(Predicted)
color :Brown to black
Density :1.416±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble to 20 mM in DMSO and to 5 mM in ethanol
form :Black-purple solid
pka :-1.63±0.20(Predicted)
color :Brown to black
Safety Information
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Description
SET domain-containing protein 8 (SETD8) is a methyltransferase that selectively monomethylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor. Ryuvidine is an inhibitor of SETD8 (IC50 = 0.5 μM) that suppresses monomethylation of H4K20 in vitro. It less potently inhibits cyclin-dependent kinase 4 (Cdk4; IC50 = 6 μM for Cdk4/cyclin D1). Over several hours of treatment, ryuvidine suppresses the expression of cell division cycle 7-related kinase (Cdc7), resulting in an ATM-dependent checkpoint response and arrest of cell cycling in S phase.More related product prices
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