2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE
![2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE price.](/CAS/GIF/265312-55-8.gif)
|
- $30 - $1260
- Product name: 2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE
- CAS: 265312-55-8
- MF: C15H12N2O2S
- MW: 284.33
- EINECS:
- MDL Number:MFCD09971103
- Synonyms:2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE;RYUVIDINE;Cdk4 Inhibitor III;2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione;4,7-Benzothiazoledione, 2-methyl-5-[(4-methylphenyl)amino]-;2-methyl-5-[(4-methylphenyl)amino]benzothiazole-4,7-dione
16 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5MG
- 10mg
- 25mg
- 10
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberSYN5642
- Product descriptionRyuvidine
- Packaging50mg
- Price$757
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002654
- Product descriptionCDK4 INHIBITOR-(III) 95.00%
- Packaging5MG
- Price$495.19
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7128
- Product descriptionRyuvidine
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7128
- Product descriptionRyuvidine
- Packaging10mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7128
- Product descriptionRyuvidine
- Packaging25mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging1mg
- Price$33
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging5mg
- Price$96
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging10mg
- Price$160
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16614
- Product descriptionRyuvidine ≥95%
- Packaging25mg
- Price$317
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number219478
- Product descriptionCdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem
- Packaging5mg
- Price$245
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number2609
- Product descriptionRyuvidine ≥98%(HPLC)
- Packaging10
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number2609
- Product descriptionRyuvidine ≥98%(HPLC)
- Packaging50
- Price$852
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberR990010
- Product descriptionRyuvidine
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberR990010
- Product descriptionRyuvidine
- Packaging100mg
- Price$1260
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number464912
- Product descriptionRyuvidine
- Packaging1mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256545
- Product descriptionRyuvidine
- Packaging10mg
- Price$466
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5642 | Ryuvidine | 50mg | $757 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002654 | CDK4 INHIBITOR-(III) 95.00% | 5MG | $495.19 | 2021-12-16 | Buy |
| ApexBio Technology | B7128 | Ryuvidine | 5mg | $104 | 2021-12-16 | Buy |
| ApexBio Technology | B7128 | Ryuvidine | 10mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | B7128 | Ryuvidine | 25mg | $347 | 2021-12-16 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 1mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 5mg | $96 | 2024-03-01 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 10mg | $160 | 2024-03-01 | Buy |
| Cayman Chemical | 16614 | Ryuvidine ≥95% | 25mg | $317 | 2024-03-01 | Buy |
| Sigma-Aldrich | 219478 | Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem | 5mg | $245 | 2024-03-01 | Buy |
| Tocris | 2609 | Ryuvidine ≥98%(HPLC) | 10 | $210 | 2021-12-16 | Buy |
| Tocris | 2609 | Ryuvidine ≥98%(HPLC) | 50 | $852 | 2021-12-16 | Buy |
| TRC | R990010 | Ryuvidine | 1mg | $30 | 2021-12-16 | Buy |
| TRC | R990010 | Ryuvidine | 100mg | $1260 | 2021-12-16 | Buy |
| Usbiological | 464912 | Ryuvidine | 1mg | $290 | 2021-12-16 | Buy |
| Usbiological | 256545 | Ryuvidine | 10mg | $466 | 2021-12-16 | Buy |
Properties
Boiling point :463.8±45.0 °C(Predicted)
Density :1.416±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble to 20 mM in DMSO and to 5 mM in ethanol
form :Black-purple solid
pka :-1.63±0.20(Predicted)
color :Brown to black
Density :1.416±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble to 20 mM in DMSO and to 5 mM in ethanol
form :Black-purple solid
pka :-1.63±0.20(Predicted)
color :Brown to black
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
SET domain-containing protein 8 (SETD8) is a methyltransferase that selectively monomethylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor. Ryuvidine is an inhibitor of SETD8 (IC50 = 0.5 μM) that suppresses monomethylation of H4K20 in vitro. It less potently inhibits cyclin-dependent kinase 4 (Cdk4; IC50 = 6 μM for Cdk4/cyclin D1). Over several hours of treatment, ryuvidine suppresses the expression of cell division cycle 7-related kinase (Cdc7), resulting in an ATM-dependent checkpoint response and arrest of cell cycling in S phase.More related product prices
Related product price
- 265312-55-8
$30-1260 - 1-(2-METHYL-1,3-THIAZOL-4-YL)ETHANONE
$41-1548.26
Suppliers and manufacturers
Shenzhen Nexconn Pharmatechs Ltd
Aladdin Scientific
Tianjin shanhaijing medicine technology co., ltd
3B Pharmachem (Wuhan) International Co.,Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
EMMX Biotechnology LLC
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Changyan Chem & Tech Co., Ltd.
DC Chemicals
