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ChemicalBook >> CAS DataBase List >> 11-Piperazinyldibenzo[b,e][1,4]diazepine

11-Piperazinyldibenzo[b,e][1,4]diazepine

11-Piperazinyldibenzo[b,e][1,4]diazepine price.
  • $48 - $2395.3
  • Product name: 11-Piperazinyldibenzo[b,e][1,4]diazepine
  • CAS: 56296-18-5
  • MF: C17H18N4
  • MW: 278.35
  • EINECS:
  • MDL Number:MFCD25121806
  • Synonyms:11-Piperazinyldibenzo[b,e][1,4]diazepine;DREADD Agonist 21;11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine;DREADD agonist 1;5H-Dibenzo[b,e][1,4]diazepine, 11-(1-piperazinyl)-;Muscarinic acetylcholine receptor,schizophrenia,mAChR,Inhibitor,muscarinic,disease,inhibit,DREADD agonist21,neurodegenerative,acetylcholine,DREADD agonist 21,DREADD,neuronal,hM3Dq,DREADD agonist-21,activation,receptors;11-(Piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 10
  • 2mg
  • 1mg
  • 50
  • 5mg
  • 10mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1046CT
  • Product descriptionDREADDagonist21
  • Packaging5mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611255
  • Product descriptionDREADD Agonist 21 >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611255
  • Product descriptionDREADD Agonist 21 >98%
  • Packaging250mg
  • Price$1179.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611255
  • Product descriptionDREADD Agonist 21 >98%
  • Packaging1g
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18907
  • Product descriptionDREADD Agonist 21 ≥98%
  • Packaging1mg
  • Price$48
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18907
  • Product descriptionDREADD Agonist 21 ≥98%
  • Packaging5mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18907
  • Product descriptionDREADD Agonist 21 ≥98%
  • Packaging10mg
  • Price$210
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6102
  • Product descriptionDREADDagonist21 98.94%
  • Packaging2mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6102
  • Product descriptionDREADDagonist21 98.94%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6102
  • Product descriptionDREADDagonist21 98.94%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10039
  • Product descriptionDREADDAgonist21 >98%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10039
  • Product descriptionDREADDAgonist21 >98%
  • Packaging250mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10039
  • Product descriptionDREADDAgonist21 >98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number5548
  • Product descriptionDREADDagonist21 ≥98%(HPLC)
  • Packaging10
  • Price$203
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number5548
  • Product descriptionDREADDagonist21 ≥98%(HPLC)
  • Packaging50
  • Price$852
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD678950
  • Product descriptionDREADDAgonist21
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1046CT DREADDagonist21 5mg $245 2021-12-16 Buy
Biorbyt Ltd orb611255 DREADD Agonist 21 >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb611255 DREADD Agonist 21 >98% 250mg $1179.8 2021-12-16 Buy
Biorbyt Ltd orb611255 DREADD Agonist 21 >98% 1g $2395.3 2021-12-16 Buy
Cayman Chemical 18907 DREADD Agonist 21 ≥98% 1mg $48 2024-03-01 Buy
Cayman Chemical 18907 DREADD Agonist 21 ≥98% 5mg $117 2024-03-01 Buy
Cayman Chemical 18907 DREADD Agonist 21 ≥98% 10mg $210 2024-03-01 Buy
ChemScene CS-6102 DREADDagonist21 98.94% 2mg $84 2021-12-16 Buy
ChemScene CS-6102 DREADDagonist21 98.94% 5mg $120 2021-12-16 Buy
ChemScene CS-6102 DREADDagonist21 98.94% 10mg $180 2021-12-16 Buy
DC Chemicals DC10039 DREADDAgonist21 >98% 100mg $450 2021-12-16 Buy
DC Chemicals DC10039 DREADDAgonist21 >98% 250mg $780 2021-12-16 Buy
DC Chemicals DC10039 DREADDAgonist21 >98% 1g $1600 2021-12-16 Buy
Tocris 5548 DREADDagonist21 ≥98%(HPLC) 10 $203 2021-12-16 Buy
Tocris 5548 DREADDagonist21 ≥98%(HPLC) 50 $852 2021-12-16 Buy
TRC D678950 DREADDAgonist21 5mg $105 2021-12-16 Buy

Properties

Boiling point :470.1±55.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.8(Max Conc. mM)
Ethanol:29.61(Max Conc. mg/mL);106.39(Max Conc. mM) form :A crystalline solid
pka :8.56±0.10(Predicted)
color :Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

DREADD agonist 21 activates hM3Dq (EC50 = 1.7 nM), a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor. It does not agonize the hM3 receptor and displays relatively weaker binding affinities for serotonin 5HT2A, 5HT2C, α1A-adrenergic, and histamine H1 receptors (Kis = 66, 170, 280, and 6 nM, respectively).

Suppliers and manufacturers

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