BI-6C9
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- $55 - $900
- Product name: BI-6C9
- CAS: 791835-21-7
- MF: C23H25N3O4S2
- MW: 471.59
- EINECS:
- MDL Number:MFCD07784498
- Synonyms:N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide;Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-;N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide;Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9
13 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number8956CS
- Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
- Packaging1mg
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8956CS
- Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
- Packaging5mg
- Price$367
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005465
- Product descriptionBI-6C9 95.00%
- Packaging1MG
- Price$459
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005465
- Product descriptionBI-6C9 95.00%
- Packaging5MG
- Price$812.48
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17265
- Product descriptionBI-6C9 ≥98%
- Packaging1mg
- Price$56
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17265
- Product descriptionBI-6C9 ≥98%
- Packaging5mg
- Price$241
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17265
- Product descriptionBI-6C9 ≥98%
- Packaging10mg
- Price$429
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0029592
- Product descriptionBI-6C9 98.24%
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029592
- Product descriptionBI-6C9 98.24%
- Packaging10mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0029592
- Product descriptionBI-6C9 98.24%
- Packaging50mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberB0186
- Product descriptionBI-6C9 ≥97% (HPLC), solid
- Packaging1mg
- Price$93.4
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberB0186
- Product descriptionBI-6C9 ≥97% (HPLC), solid
- Packaging5mg
- Price$324
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberB591705
- Product descriptionBI-6C9
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8956CS | N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide | 1mg | $159 | 2021-12-16 | Buy |
| AK Scientific | 8956CS | N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide | 5mg | $367 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005465 | BI-6C9 95.00% | 1MG | $459 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005465 | BI-6C9 95.00% | 5MG | $812.48 | 2021-12-16 | Buy |
| Cayman Chemical | 17265 | BI-6C9 ≥98% | 1mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 17265 | BI-6C9 ≥98% | 5mg | $241 | 2024-03-01 | Buy |
| Cayman Chemical | 17265 | BI-6C9 ≥98% | 10mg | $429 | 2024-03-01 | Buy |
| ChemScene | CS-0029592 | BI-6C9 98.24% | 5mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-0029592 | BI-6C9 98.24% | 10mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-0029592 | BI-6C9 98.24% | 50mg | $900 | 2021-12-16 | Buy |
| Sigma-Aldrich | B0186 | BI-6C9 ≥97% (HPLC), solid | 1mg | $93.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | B0186 | BI-6C9 ≥97% (HPLC), solid | 5mg | $324 | 2024-03-01 | Buy |
| TRC | B591705 | BI-6C9 | 1mg | $55 | 2021-12-16 | Buy |
Properties
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 24 mg/mL, soluble
form :solid
pka :11.58±0.50(Predicted)
color :off-white
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 24 mg/mL, soluble
form :solid
pka :11.58±0.50(Predicted)
color :off-white
Safety Information
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Description
BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.Suppliers and manufacturers
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