BMS-265246
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- $52 - $2600
- Product name: BMS-265246
- CAS: 582315-72-8
- MF: C18H17F2N3O2
- MW: 345.34
- EINECS:
- MDL Number:MFCD22420825
- Synonyms:BMS-265246;BMS-265246, >=98%;(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)-methanone;(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)-methanone BMS265246;BMS265246; BMS 265246;CS-984;Methanone, (4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)-;BMS-265246 USP/EP/BP
27 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mM(in 1mL DMSO)
- 10mg
- 50
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2276AH
- Product description(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-(2,6-difluoro-4-methylphenyl)methanone
- Packaging10mg
- Price$459
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging1mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging5mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging10mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging25mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging50mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging100mg
- Price$247
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging250mg
- Price$371
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA107996
- Product descriptionBMS-265246 98+%
- Packaging1g
- Price$926
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8385
- Product descriptionBMS265246
- Packaging5mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8385
- Product descriptionBMS265246
- Packaging10mM(in 1mL DMSO)
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19168
- Product descriptionBMS-265246 ≥95%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19168
- Product descriptionBMS-265246 ≥95%
- Packaging5mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0922
- Product descriptionBMS-265246 99.28%
- Packaging5mg
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0922
- Product descriptionBMS-265246 99.28%
- Packaging10mg
- Price$365
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0922
- Product descriptionBMS-265246 99.28%
- Packaging50mg
- Price$970
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2276AH | (4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-(2,6-difluoro-4-methylphenyl)methanone | 10mg | $459 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 1mg | $52 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 5mg | $86 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 10mg | $112 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 25mg | $146 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 50mg | $190 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 100mg | $247 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 250mg | $371 | 2021-12-16 | Buy |
| Ambeed | A107996 | BMS-265246 98+% | 1g | $926 | 2021-12-16 | Buy |
| ApexBio Technology | A8385 | BMS265246 | 5mg | $189 | 2021-12-16 | Buy |
| ApexBio Technology | A8385 | BMS265246 | 10mM(in 1mL DMSO) | $209 | 2021-12-16 | Buy |
| Cayman Chemical | 19168 | BMS-265246 ≥95% | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 19168 | BMS-265246 ≥95% | 5mg | $270 | 2024-03-01 | Buy |
| ChemScene | CS-0922 | BMS-265246 99.28% | 5mg | $228 | 2021-12-16 | Buy |
| ChemScene | CS-0922 | BMS-265246 99.28% | 10mg | $365 | 2021-12-16 | Buy |
| ChemScene | CS-0922 | BMS-265246 99.28% | 50mg | $970 | 2021-12-16 | Buy |
Properties
Boiling point :552.9±50.0 °C(Predicted)
Density :1.304±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL in DMSO
form :solid
pka :8.50±0.40(Predicted)
color :White to pink
Density :1.304±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL in DMSO
form :solid
pka :8.50±0.40(Predicted)
color :White to pink
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. BMS-265246 is a cell-permeable inhibitor of Cdk1/cyclin B and Cdk2/cyclin E (IC50s = 6 and 9 nM, respectively). It less potently inhibits Cdk4/cyclin D (IC50 = 0.23 μM). BMS-265246 blocks the cycling of HCT-116 cells (EC50 = 0.29-0.49 μM), resulting in cell cycle arrest in G2 phase.Related product price
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