PF 04995274
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- $34 - $2450
- Product name: PF 04995274
- CAS: 1331782-27-4
- MF: C23H32N2O6
- MW: 432.51
- EINECS:
- MDL Number:
- Synonyms:PF 04995274;PF-04995274 >=98% (HPLC);2H-Pyran-4-ol, tetrahydro-4-[[4-[[[4-[[(3R)-tetrahydro-3-furanyl]oxy]-1,2-benzisoxazol-3-yl]oxy]methyl]-1-piperidinyl]methyl]-;PF04995274;PF 04995274;4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol;Inhibitor,5-HT4,5-hydroxytryptamine Receptor,behavior,Alzheimer′s disease,PF-04995274,inhibit,PF04995274,Serotonin Receptor,5-HT Receptor,Stress-induced,PF 04995274,depressive-like;(R)-4-((4-(((4-((Tetrahydrofuran-3-yl)oxy)benzo[d]isoxazol-3-yl)oxy)methyl)piperidin-1-yl)methyl)tetrahydro-2H-pyran-4-ol
14 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number6654DK
- Product descriptionPF-04995274
- Packaging1mg
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6654DK
- Product descriptionPF-04995274
- Packaging10mg
- Price$301
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28776
- Product descriptionPF-04995274
- Packaging1mg
- Price$34
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28776
- Product descriptionPF-04995274
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28776
- Product descriptionPF-04995274
- Packaging10mg
- Price$183
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28776
- Product descriptionPF-04995274
- Packaging25mg
- Price$412
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0007316
- Product descriptionPF-04995274 99.42%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0007316
- Product descriptionPF-04995274 99.42%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0007316
- Product descriptionPF-04995274 99.42%
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0007316
- Product descriptionPF-04995274 99.42%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0007316
- Product descriptionPF-04995274 99.42%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9915
- Product descriptionPF-04995274 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9915
- Product descriptionPF-04995274 >98%
- Packaging250mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9915
- Product descriptionPF-04995274 >98%
- Packaging1g
- Price$2450
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6654DK | PF-04995274 | 1mg | $136 | 2021-12-16 | Buy |
| AK Scientific | 6654DK | PF-04995274 | 10mg | $301 | 2021-12-16 | Buy |
| Cayman Chemical | 28776 | PF-04995274 | 1mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 28776 | PF-04995274 | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 28776 | PF-04995274 | 10mg | $183 | 2024-03-01 | Buy |
| Cayman Chemical | 28776 | PF-04995274 | 25mg | $412 | 2024-03-01 | Buy |
| ChemScene | CS-0007316 | PF-04995274 99.42% | 5mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-0007316 | PF-04995274 99.42% | 10mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-0007316 | PF-04995274 99.42% | 25mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-0007316 | PF-04995274 99.42% | 50mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-0007316 | PF-04995274 99.42% | 100mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC9915 | PF-04995274 >98% | 100mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC9915 | PF-04995274 >98% | 250mg | $1200 | 2021-12-16 | Buy |
| DC Chemicals | DC9915 | PF-04995274 >98% | 1g | $2450 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:20.0(Max Conc. mg/mL);46.2(Max Conc. mM)
form :A crystalline solid
color :White to off-white
solubility :DMSO:20.0(Max Conc. mg/mL);46.2(Max Conc. mM)
form :A crystalline solid
color :White to off-white
Safety Information
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Description
PF-04995274 is a partial agonist of the serotonin (5-HT) receptor subtypes 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E (Kis = 0.36, 0.46, 0.15, and 0.32 nM, respectively, in a radioligand binding assay). It increases cAMP levels in HEK293 cells expressing 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E receptors (EC50s = 0.47, 0.36, 0.37, and 0.26 nM, respectively, for the human recombinant receptors). PF-04995274 decreases scopolamine-induced increases in the distance traveled in the Morris water maze in rats when administered at a dose of 0.032 mg/kg.More related product prices
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