VX 702
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- $25 - $5328
- Product name: VX 702
- CAS: 745833-23-2
- MF: C19H12F4N4O2
- MW: 404.32
- EINECS:
- MDL Number:MFCD11616590
- Synonyms:6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide;VX 702;6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide VX-702;VX 702 6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide;VX702;VX-702;2-(2,4-Difluorophenyl)-6-(1-(2,6-difluorophenyl)ureido)nicotinamide;(479543-46-9) vx 702;CS-1840
30 prices
Selected condition：
Brand
- Adipogen Life Sciences
- Apolloscientific
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TCI Chemical
- TRC
- Usbiological
Package
- 2mg
- 2.5mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 5g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1093-M100
- Product descriptionVX-702 ≥95%
- Packaging100mg
- Price$378
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0171
- Product descriptionVX-702
- Packaging10mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0171
- Product descriptionVX-702
- Packaging50mg
- Price$247
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBISN0171
- Product descriptionVX-702
- Packaging100mg
- Price$443
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60370
- Product descriptionVX-702 ≥98%
- Packaging20mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546011
- Product descriptionVX-702 >98%
- Packaging10mg
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546011
- Product descriptionVX-702 >98%
- Packaging50mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154628
- Product descriptionVX-702 (VX702) >98%
- Packaging100mg
- Price$397.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154628
- Product descriptionVX-702 (VX702) >98%
- Packaging250mg
- Price$606.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154628
- Product descriptionVX-702 (VX702) >98%
- Packaging1g
- Price$1504.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFV28726
- Product descriptionVX 702
- Packaging50mg
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFV28726
- Product descriptionVX 702
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13108
- Product descriptionVX-702 ≥95%
- Packaging5mg
- Price$25
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13108
- Product descriptionVX-702 ≥95%
- Packaging10mg
- Price$45
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13108
- Product descriptionVX-702 ≥95%
- Packaging25mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0074
- Product descriptionVX-702 99.75%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1093-M100 | VX-702 ≥95% | 100mg | $378 | 2021-12-16 | Buy |
| Apolloscientific | BISN0171 | VX-702 | 10mg | $86 | 2021-12-16 | Buy |
| Apolloscientific | BISN0171 | VX-702 | 50mg | $247 | 2021-12-16 | Buy |
| Apolloscientific | BISN0171 | VX-702 | 100mg | $443 | 2021-12-16 | Buy |
| Arctom | CFN60370 | VX-702 ≥98% | 20mg | $168 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546011 | VX-702 >98% | 10mg | $136 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546011 | VX-702 >98% | 50mg | $340 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154628 | VX-702 (VX702) >98% | 100mg | $397.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154628 | VX-702 (VX702) >98% | 250mg | $606.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154628 | VX-702 (VX702) >98% | 1g | $1504.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FV28726 | VX 702 | 50mg | $263 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FV28726 | VX 702 | 10mg | $75 | 2021-12-16 | Buy |
| Cayman Chemical | 13108 | VX-702 ≥95% | 5mg | $25 | 2024-03-01 | Buy |
| Cayman Chemical | 13108 | VX-702 ≥95% | 10mg | $45 | 2024-03-01 | Buy |
| Cayman Chemical | 13108 | VX-702 ≥95% | 25mg | $107 | 2024-03-01 | Buy |
| ChemScene | CS-0074 | VX-702 99.75% | 10mg | $60 | 2021-12-16 | Buy |
Properties
Boiling point :555.2±60.0 °C(Predicted)
Density :1.503
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 2 mg/ml)
form :solid
pka :10.65±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
CAS DataBase Reference :745833-23-2
Density :1.503
storage temp. :-20°C
solubility :Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 2 mg/ml)
form :solid
pka :10.65±0.50(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
CAS DataBase Reference :745833-23-2
Safety Information
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Description
VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38α and p38β (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1β, and TNF-α production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml, respectively. VX-702, at 1 μM, inhibits activation of p38 in platelets by thrombin, U-46619 , or collagen but does not block platelet aggregation in response to collagen. Although orally active, VX-702 provides only transient suppression of biomarkers of inflammation in ongoing rheumatoid arthritis.More related product prices
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