PD 0332991 HCl
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- $28 - $1208.7
- Product name: PD 0332991 HCl
- CAS: 827022-32-2
- MF: C24H30ClN7O2
- MW: 484
- EINECS:1592732-453-0
- MDL Number:MFCD22420809
- Synonyms:PD 0332991 HCl;PALBOCICLIB HCL; PD0332991 HCL;6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride Palbociclib (PD-0332991) HCl;Palbociclib hydrochloride, >=98%;PD-0332991 (Palbociclib);PD 0332991 hydrochloride;Palbociclib HCl;Palbociclib (hydrochloride)
28 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Usbiological
Package
- 1mg
- 1unit
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product numberX7620
- Product descriptionPalbociclibHCl
- Packaging1g
- Price$309
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA165771
- Product description6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+%
- Packaging5mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA165771
- Product description6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+%
- Packaging10mg
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA165771
- Product description6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+%
- Packaging50mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA165771
- Product description6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+%
- Packaging100mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA165771
- Product description6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+%
- Packaging250mg
- Price$152
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA165771
- Product description6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+%
- Packaging1g
- Price$382
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8316
- Product descriptionPD0332991(Palbociclib)HCl
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146249
- Product descriptionPalbociclib (PD0332991 HCl) >99%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146249
- Product descriptionPalbociclib (PD0332991 HCl) >99%
- Packaging250mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146249
- Product descriptionPalbociclib (PD0332991 HCl) >99%
- Packaging1g
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP137711
- Product descriptionPD 0332991 hydrochloride
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP137711
- Product descriptionPD 0332991 hydrochloride
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16273
- Product descriptionPD 0332991 (hydrochloride) ≥95%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16273
- Product descriptionPD 0332991 (hydrochloride) ≥95%
- Packaging5mg
- Price$108
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16273
- Product descriptionPD 0332991 (hydrochloride) ≥95%
- Packaging10mg
- Price$195
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X7620 | PalbociclibHCl | 1g | $309 | 2021-12-16 | Buy |
| Ambeed | A165771 | 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+% | 5mg | $28 | 2021-12-16 | Buy |
| Ambeed | A165771 | 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+% | 10mg | $37 | 2021-12-16 | Buy |
| Ambeed | A165771 | 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+% | 50mg | $63 | 2021-12-16 | Buy |
| Ambeed | A165771 | 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+% | 100mg | $100 | 2021-12-16 | Buy |
| Ambeed | A165771 | 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+% | 250mg | $152 | 2021-12-16 | Buy |
| Ambeed | A165771 | 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-onehydrochloride1 98+% | 1g | $382 | 2021-12-16 | Buy |
| ApexBio Technology | A8316 | PD0332991(Palbociclib)HCl | 1unit | $28 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146249 | Palbociclib (PD0332991 HCl) >99% | 100mg | $414.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146249 | Palbociclib (PD0332991 HCl) >99% | 250mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146249 | Palbociclib (PD0332991 HCl) >99% | 1g | $1208.7 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP137711 | PD 0332991 hydrochloride | 10mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP137711 | PD 0332991 hydrochloride | 50mg | $437.5 | 2021-12-16 | Buy |
| Cayman Chemical | 16273 | PD 0332991 (hydrochloride) ≥95% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 16273 | PD 0332991 (hydrochloride) ≥95% | 5mg | $108 | 2024-03-01 | Buy |
| Cayman Chemical | 16273 | PD 0332991 (hydrochloride) ≥95% | 10mg | $195 | 2024-03-01 | Buy |
Properties
storage temp. := -70C
solubility :≥14.48 mg/mL in H2O; ≥2.42 mg/mL in DMSO; ≥2.79 mg/mL in EtOH with gentle warming and ultrasonic
form :Yellow liquid
color :Light yellow to yellow
solubility :≥14.48 mg/mL in H2O; ≥2.42 mg/mL in DMSO; ≥2.79 mg/mL in EtOH with gentle warming and ultrasonic
form :Yellow liquid
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
PD 0332991 is an orally active, selective inhibitor of the cyclin D kinases Cdk4 (IC50 = 11 nM) and Cdk6 (IC50= 16 nM) with no activity against a panel of 36 additional protein kinases. It has been reported to have antiproliferative activity against retinoblastoma-positive tumor cells, blocking retinoblastoma phosphorylation and inducing G1 arrest at nanomolar concentrations. PD 0332991 can inhibit the growth of certain ER-positive or HER2-amplified breast cancer cells (IC50s as low as 4 nM) and demonstrates synergy with tamoxifen and trastuzumab, respectively. Recently, PD 0332991 inhibition of Cdk4 activity has been used to demonstrate a role for insulin-activated cyclinD1-Cdk4 signaling in the control of glucose metabolism that is independent of cell cycle progression.More related product prices
PD0332991 Isethionate 779353-01-4 871700-17-3 LEE011 MK-2206 2HCl 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER OTAVA-BB 1115529 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril 89-25-8 Flupirtine maleate 3382-63-6 16133-25-8 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)- (4S)-3-[(5R)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLIDIN-2-ONE OTAVA-BB 1207229 Olaparib LY2835219Related product price
- PD0332991 Isethionate
$40-2220 - 779353-01-4
$28-3728.1 - 871700-17-3
$28-4391.1
