11-DEOXY PROSTAGLANDIN E1

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Products Intro: Product Name:11-deoxy Prostaglandin E1
CAS:37786-00-8
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CAS:37786-00-8
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CAS:37786-00-8
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Products Intro: Product Name:11-DEOXY PROSTAGLANDIN E1
CAS:37786-00-8
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11-DEOXY PROSTAGLANDIN E1 manufacturers

11-DEOXY PROSTAGLANDIN E1 Basic information
Product Name:11-DEOXY PROSTAGLANDIN E1
Synonyms:11-DEOXY PROSTAGLANDIN E1;9-OXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID;7-((1R,2R)-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)heptanoic acid;11-deoxy Prostaglandin E1 Exclusive;Prost-13-en-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-
CAS:37786-00-8
MF:C20H34O4
MW:338.48
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Mol File:37786-00-8.mol
11-DEOXY PROSTAGLANDIN E1 Structure
11-DEOXY PROSTAGLANDIN E1 Chemical Properties
Boiling point 509.7±35.0 °C(Predicted)
density 1.070±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
form A crystalline solid
pka4.77±0.10(Predicted)
Safety Information
MSDS Information
11-DEOXY PROSTAGLANDIN E1 Usage And Synthesis
Uses11-Deoxy prostaglandin E1 (AY-23578; Doproston B) is an analog of prostaglandin E1 (PGE1) with bronchodilator activity. 11-Deoxy prostaglandin E1 inhibits histamine-induced bronchoconstriction and causes relaxation of tracheal strips in isolated guinea pigs[1].
DefinitionChEBI: 11-deoxyprostaglandin E1 is a prostanoid.
in vivo

11-Deoxy prostaglandin E1 (administered as a spray) has no significant bronchodilator effect in guinea pigs and cats[1].

References[1] Greenberg R, et al. The bronchodilator acitivity of an 11-deoxyprostaglandin (AY 23 578). Can J Physiol Pharmacol. 1975 Oct;53(5):799-809. DOI:10.1139/y75-110
11-DEOXY PROSTAGLANDIN E1 Preparation Products And Raw materials
Tag:11-DEOXY PROSTAGLANDIN E1(37786-00-8) Related Product Information
13,14-DIHYDRO-15(R)-PROSTAGLANDIN E1 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 13,14-DIHYDROPROSTAGLANDIN E1 11BETA-PROSTAGLANDIN E1 ORNOPROSTIL Prostaglandin E1 11-DEOXY PROSTAGLANDIN E1 9-OXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC-3,3,4,4-D4 ACID 9,11-DIOXO-15S-HYDROXY-PROST-13E-EN-1-OIC ACID 19(R)-HYDROXY PROSTAGLANDIN E1 6,9-DIOXO-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID 16,16-DIMETHYL PROSTAGLANDIN E1 16,16-DIMETHYL-6-KETO PROSTAGLANDIN E1 15(S)-15-METHYL PROSTAGLANDIN E1 Mexiprostil MR 356 PROSTAGLANDIN E1-[5,6-3H(N)] PROSTGLANDIN E1-ALPHA-CYCLODEXTRIN COMPLEX

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