15(R)-PROSTAGLANDIN E1

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Products Intro: Product Name:13,14-Dihydroprostaglandin E1
CAS:19313-28-1
Purity:>=98% Package:$118.9/1mg;$764.9/10mg;Bulk package Remarks:98%
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
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Products Intro: Product Name:13,14-DIHYDROPROSTAGLANDIN E1
CAS:19313-28-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: ChemStrong Scientific Co.,Ltd  
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Products Intro: Product Name:13,14-dihydro Prostaglandin E1
CAS:19313-28-1
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
Company Name: Shanghai Synchem Pharma Co., ltd  
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Products Intro: Product Name:13,14-DIHYDROPROSTAGLANDIN E1
CAS:19313-28-1
Purity:95%+
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
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Products Intro: Product Name:Prostaglandin E0
CAS:19313-28-1
Purity:98% (TLC) Package:500μg;1mg;5mg
15(R)-PROSTAGLANDIN E1 Basic information
Product Name:15(R)-PROSTAGLANDIN E1
Synonyms:9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC ACID;13,14-DIHYDROPROSTAGLANDIN E1;PGE0;13,14-Dihydroprostaglandinee1;13,14-dihydro PGE1;7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoctyl]-5-oxocyclopentyl]heptanoic acid;(11R)-11α,15α-Dihydroxy-9-oxoprostan-1-oic acid;13,14-Dihydro-prostaglandin E1 (PGE0)
CAS:19313-28-1
MF:C20H36O5
MW:356.5
EINECS:
Product Categories:
Mol File:19313-28-1.mol
15(R)-PROSTAGLANDIN E1 Structure
15(R)-PROSTAGLANDIN E1 Chemical Properties
Boiling point 541.4±35.0 °C(Predicted)
density 1.075±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Ethyl Acetate, Methanol, Tetrahydrofuran
form Colorless to pale yellow oil
pka4.77±0.10(Predicted)
Stability:Volatile
Safety Information
MSDS Information
15(R)-PROSTAGLANDIN E1 Usage And Synthesis
Description13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.
UsesProstaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and can inhibit aggregation, ATP release, and thromboxane generation by human platelets. Prostaglandin E0 can also decrease the formation of cyclooxygenase (COX) metabolites by inhibiting the induction of COX-2 protein by LPS.
DefinitionChEBI: 13,14-Dihydro PGE1 is a prostanoid.
15(R)-PROSTAGLANDIN E1 Preparation Products And Raw materials
Tag:15(R)-PROSTAGLANDIN E1(19313-28-1) Related Product Information
PROSTAGLANDIN F1ALPHA Latanoprost Misoprostol Acid 8-[(3S,4S)-4α-[(Z)-2-Pentenyl]-5-oxo-1-cyclopentene-3α-yl]octanoic acid 15-Hydroxy Lubiprostone 13,14-DIHYDRO-15(R)-PROSTAGLANDIN E1 11BETA-PROSTAGLANDIN E1 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 11-DEOXY PROSTAGLANDIN E1 13,14-DIHYDRO PROSTAGLANDIN E1-D4 13,14-DIHYDRO-19(R)-HYDROXY PROSTAGLANDIN E1 13,14-DIHYDROPROSTAGLANDIN E1 13,14-Dihydroprostaglandin F2α 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 15-keto-13,14-dihydroprostaglandin A2 15-keto-13,14-dihydroprostaglandin E2-thyroglobulin conjugate 2,3-dinor-6,15-diketo-13,14-dihydroprostaglandin F1alpha 13,14-dihydroprostaglandin E2