13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1

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Products Intro: Product Name:13,14-dihydro-15-keto Prostaglandin E1
CAS:5094-14-4
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CAS:5094-14-4
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CAS:5094-14-4
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CAS:5094-14-4
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CAS:5094-14-4
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13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 Basic information
Product Name:13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1
Synonyms:13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1;9,15-DIOXO-11ALPHA-HYDROXY-PROSTAN-1-OIC ACID;CDUVSQMTLOYKTR-ZHALLVOQSA-N;13,14-dihydro-15-keto PGE1;9,15-dioxo-11α-hydroxy-prostan-1-oic acid;U 21002;Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11α)-;15-Keto Prostaglandin E0 DISCONTINUED, OFFER K202056
CAS:5094-14-4
MF:C20H34O5
MW:354.49
EINECS:
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Mol File:5094-14-4.mol
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 Structure
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 Chemical Properties
Boiling point 537.2±35.0 °C(Predicted)
density 1.072±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), THF (Slightly)
form Oil
pka4.77±0.10(Predicted)
color Dark Yellow
Safety Information
MSDS Information
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 Usage And Synthesis
Description13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. 13,14-dihydro-15-keto PGE1 is a weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 μM, respectively, compared to PGE1 which has an IC50 of 40 nM.
Uses15-Keto Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and has been shown to induce arterial thromboresistance in experimental animals and in man, but with several magnitudes higher concentrations than Prostaglandin E1. 15-Keto Prostaglandin E0 is also used as the active ingredient in compositions used for the treatment of external secretion disorders.
DefinitionChEBI: 13,14-dihydro-15-oxoprostaglandin E1 is a prostaglandin E obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin E1. It has a role as a human xenobiotic metabolite. It is functionally related to a prostaglandin E1. It is a conjugate acid of a 13,14-dihydro-15-oxoprostaglandin E1(1-).
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 Preparation Products And Raw materials
Tag:13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1(5094-14-4) Related Product Information
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