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6-Chloropurine

6-Chloropurine Suppliers list
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:6-Chloropurine
CAS:87-42-3
Purity:0.98 Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Xinxiang Aurora Biotechnology Co.,Ltd.
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Products Intro: Product Name:6-Chloropurine
CAS:87-42-3
Purity:98% Package:25Kg
Company Name: Hebei Chuanghai Biotechnology Co., Ltd
Tel: +86-15531157085 +86-15531157085
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Products Intro: Product Name:6-Chloropurine
CAS:87-42-3
Purity:99% Package:1KG;10.00;USD
Company Name: Hebei Mujin Biotechnology Co.,Ltd
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Products Intro: Product Name:6-Chloropurine
CAS:87-42-3
Purity:99% Package:25KG
Company Name: Shaanxi Didu New Materials Co. Ltd
Tel: +86-89586680 +86-13289823923
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Products Intro: Product Name:6-Chloropurine
CAS:87-42-3
Purity:99.0% Min Package:1g;1.5USD

6-Chloropurine manufacturers

  • 6-Chloropurine
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  • $0.00 / 25Kg
  • 2025-04-03
  • CAS:87-42-3
  • Min. Order: 1Kg
  • Purity: 98%
  • Supply Ability: 20Ton
  • 6-Chloropurine
  • 6-Chloropurine pictures
  • $0.00 / 1kg
  • 2025-04-03
  • CAS:87-42-3
  • Min. Order: 1kg
  • Purity: 98
  • Supply Ability: 1000
  • 6-Chloropurine
  • 6-Chloropurine pictures
  • $0.00 / 1kg
  • 2025-04-02
  • CAS:87-42-3
  • Min. Order: 1kg
  • Purity: 98%min
  • Supply Ability: 1000kg
6-Chloropurine Chemical Properties
Melting point >300 °C (dec.) (lit.)
Boiling point 254.17°C (rough estimate)
density 1.4649 (rough estimate)
refractive index 1.8430 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility 5 g/L
pka7.47±0.20(Predicted)
form crystalline
color yellow-orange
biological sourcemouse
Water Solubility 5 g/L
Merck 14,2161
BRN 5774
InChIKeyZKBQDFAWXLTYKS-UHFFFAOYSA-N
CAS DataBase Reference87-42-3(CAS DataBase Reference)
NIST Chemistry Reference6-Chloropurine(87-42-3)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38-20/21/22
Safety Statements 26-36-36/37/39
WGK Germany 3
RTECS UO7520000
10-23
HazardClass IRRITANT
HS Code 29335990
ToxicityLD50 oral in mouse: 720mg/kg
MSDS Information
ProviderLanguage
6-Chloropurine English
SigmaAldrich English
ACROS English
ALFA English
6-Chloropurine Usage And Synthesis
Chemical PropertiesIt is a pale yellow crystal with relatively stable chemical properties that do not cause decomposition at room temperature. Its structure includes nitrogen heterocycles, which give rise to remarkable alkalinity and the formation of volatile acid salts. It is soluble in dimethyl sulfoxide, but has only slight solubility in water.
Uses6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide. It is also used to prepare 6-succinoaminopurine.
DefinitionChEBI: 6-Chloro-1H-purine is a member of purines. It is metabolized to form 6-mercaptopurine and has been used as an antineoplastic.
Preparation6-chloropurine is synthesized by reacting hypoxanthine with phosphoryl chloride in the presence of an unreactive base such as dimethyl aniline. It may likewise be formed by heating hypoxanthine under pressure with phosphoryl chloride as well as with a reagent prepared by adding water, preferably about by volume, to dry phosphoryl chloride.
US2832781A
Synthesis Reference(s)Journal of the American Chemical Society, 78, p. 1928, 1956 DOI: 10.1021/ja01590a043
General DescriptionThe acid-catalyzed reaction of 6-chloropurine with 3,4-di-O-acetyl-D-xylal has been investigated.
Purification Methods6-Chloropurine crystallises from water. The UV in water at pH 1 has 264nm (log 3.94). [Beilstein 26 III/IV 1742.]
Tag:6-Chloropurine(87-42-3) Related Product Information
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