Company Name: |
Shanghai Chaolan Chemical Technology Center
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QQ:65489617 15618227136 |
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info@SuperLan-chem.com |
Products Intro: |
Product Name:PROTAC ER Degrader-4 CAS:2361114-15-8 Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G,500G
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| PROTAC ER Degrader-4 Basic information |
| PROTAC ER Degrader-4 Chemical Properties |
Boiling point | 1038.9±65.0 °C(Predicted) | density | 1.254±0.06 g/cm3(Predicted) | pka | 13.54±0.46(Predicted) | form | Solid | color | Light yellow to yellow |
| PROTAC ER Degrader-4 Usage And Synthesis |
Biological Activity | PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].
PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM in the MCF-7 ER degradation cellular assay[1]. | References | [1]. Bin Yang, et al. Compounds and their use in treating cancer. WO2019123367A1. |
| PROTAC ER Degrader-4 Preparation Products And Raw materials |
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