Company Name: |
Sichuan Wei Keqi Biological Technology Co., Ltd.
|
Tel: |
028-81700200 18116577057 |
Email: |
3003855609@qq.com |
Products Intro: |
Product Name:PROTACCDK9Degrader-1 CAS:2118356-96-8 Purity:98% Package:5mg;10mg;20mg;50mg;100mg;200mg;500mg;1g
|
CDK9-PROTAC manufacturers
- CDK9-PROTAC
-
- $0.00 / 1mg
-
2024-10-14
- CAS:2118356-96-8
- Min. Order: 1mg
- Purity: 98%min
- Supply Ability: 500mg
|
| CDK9-PROTAC Basic information |
Product Name: | CDK9-PROTAC | Synonyms: | CDK9-PROTAC;PROTAC 6;PROTAC CDK9 DEGRADER-1;N-(5-Cyclobutyl-1H-pyrazol-3-yl)-2-(4-((5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)pentyl)oxy)phenyl)acetamide;Benzeneacetamide, N-(5-cyclobutyl-1H-pyrazol-3-yl)-4-[[5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]pentyl]oxy]-;N-(5-cyclobutyl-1H-pyrazol-3-yl)-2-{4-[(5-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}pentyl)oxy]phenyl}acetamide | CAS: | 2118356-96-8 | MF: | C33H35N5O7 | MW: | 613.66 | EINECS: | | Product Categories: | | Mol File: | 2118356-96-8.mol | |
| CDK9-PROTAC Chemical Properties |
Boiling point | 947.1±65.0 °C(Predicted) | density | 1.390±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO : ≥ 104 mg/mL (169.47 mM) | form | Solid | pka | 10.70±0.40(Predicted) | color | White to off-white |
| CDK9-PROTAC Usage And Synthesis |
Uses | CDK9-PROTAC can be used as a selective CDK9 degrader. | Biological Activity | PROTAC CDK9 Degrader-1 is a selective CDK9 degrader. | in vitro | PROTAC CDK9 Degrader-1 (Compound 3; 2.5-20 μM; 6 hours) degrades CDK9 in a dose dependent manner in HCT116 cells. p> Western Blot Analysis Cell Line: | HCT116 cells | Concentration: | 2.5, 5, 10, and 20μM | Incubation Time: | 6 hours | Result: | Degraded CDK9 in a dose dependent manner . | | target | |
| CDK9-PROTAC Preparation Products And Raw materials |
|