Company Name: |
Sichuan Wei Keqi Biological Technology Co., Ltd.
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Tel: |
028-81700200 18116577057 |
Email: |
3003855609@qq.com |
Products Intro: |
Product Name:PROTACFLT-3degrader1/FLT3PROTAC CAS:2230826-81-8 Purity:98% Package:5mg;10mg;20mg;50mg;100mg;200mg;500mg;1g
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Company Name: |
Shanghai Chaolan Chemical Technology Center
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Tel: |
QQ:65489617 15618227136 |
Email: |
info@SuperLan-chem.com |
Products Intro: |
Product Name:PROTAC FLT-3 degrader 1 CAS:2230826-81-8 Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G,500G
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| PROTAC FLT-3 degrader 1 Basic information |
| PROTAC FLT-3 degrader 1 Chemical Properties |
density | 1.38±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMSO : 150 mg/mL (147.03 mM; Need ultrasonic) | form | Solid | pka | 12.59±0.70(Predicted) | color | White to light yellow |
| PROTAC FLT-3 degrader 1 Usage And Synthesis |
Biological Activity | PROTAC FLT-3 degrader 1 is a von Hippel-Lindau-based PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction[1]. | References | [1]. Burslem GM, et al. Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion. J Am Chem Soc. 2018 Dec 5;140(48):16428-16432. |
| PROTAC FLT-3 degrader 1 Preparation Products And Raw materials |
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