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Lynnchem
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86-(0)29-85992781 17792393971 |
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| Products Intro: |
Product Name:KAZUSAMYCIN A FROM STREPTOMYCES SP.
CAS:92090-94-3
Purity:>95% by HPLC Package:1mg;5mg
|
| Company Name: |
Novachemistry
|
| Tel: |
44-20819178-90 02081917890 |
| Email: |
info@novachemistry.com |
| Products Intro: |
Product Name:Kazusamycin A
CAS:92090-94-3
Purity:>95% by HPLC Package:1mg;5mg
|
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| | KAZUSAMYCIN A FROM STREPTOMYCES SP. Basic information |
| Product Name: | KAZUSAMYCIN A FROM STREPTOMYCES SP. | | Synonyms: | KAZUSAMYCIN A FROM STREPTOMYCES SP.;antibiotic81-484;antibioticcl1957b;kazusamycin;kazusamycina;19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-2,10,12,16,18-nonadecapentenoic acid;PD-114721;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, (2E,10E,12E,16Z,18E)- | | CAS: | 92090-94-3 | | MF: | C33H48O7 | | MW: | 556.73 | | EINECS: | | | Product Categories: | | | Mol File: | 92090-94-3.mol |  |
| | KAZUSAMYCIN A FROM STREPTOMYCES SP. Chemical Properties |
| Boiling point | 761.5±60.0 °C(Predicted) | | density | 1.109±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | methanol/water: 7:3, soluble | | form | aqueous methanol solution | | pka | 5.10±0.33(Predicted) |
| | KAZUSAMYCIN A FROM STREPTOMYCES SP. Usage And Synthesis |
| Uses | Kazusamycin A is a potent antibiotic shown to induce G2 cell cycle arrest and delay M phase. | | Uses | Kazusamycin A is a minor member of the leptomycin complex isolated from some Streptomyces species. It is an hydroxylated analogue of leptomycin B, a nuclear export inhibitor. Kazusamycin A exhibits potent antitumour activity both in vitro and in vivo against P388 and L1210 cell lines, and also shows strong antibacterial and antifungal activity. |
| | KAZUSAMYCIN A FROM STREPTOMYCES SP. Preparation Products And Raw materials |
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