PAGOCLONE manufacturers
- Pagoclone
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- $1.00 / 1g
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2025-03-29
- CAS:133737-32-3
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100kg
- PAGOCLONE
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- $0.00 / 1kg
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2025-03-18
- CAS:133737-32-3
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10T
- PAGOCLONE
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- $0.00 / 1Kg
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2024-12-24
- CAS:133737-32-3
- Min. Order: 1Kg
- Purity: 99.9%
- Supply Ability: 20 tons
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| | PAGOCLONE Basic information |
| Product Name: | PAGOCLONE | | Synonyms: | 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;RP 59037;Ip 456;Rp 62955;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;(+)-RP-59037; IP-456; RP-62955; CI-1043;CI-1043;AGOCLONE | | CAS: | 133737-32-3 | | MF: | C23H22ClN3O2 | | MW: | 407.89 | | EINECS: | 225-799-5 | | Product Categories: | | | Mol File: | 133737-32-3.mol |  |
| | PAGOCLONE Chemical Properties |
| Boiling point | 582.1±50.0 °C(Predicted) | | density | 1.273±0.06 g/cm3(Predicted) | | pka | 1.62±0.30(Predicted) | | form | Solid | | color | White to off-white | | InChI | InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3 | | InChIKey | HIUPRQPBWVEQJJ-UHFFFAOYSA-N | | SMILES | C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2 |
| | PAGOCLONE Usage And Synthesis |
| Description | Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability. | | Uses | Anti-anxiety agent. | | Application | Pagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition. | | Brand name | Bextra (Interneuron). |
| | PAGOCLONE Preparation Products And Raw materials |
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