中文名:钙黄绿素乙酰氧基甲酯
英文名:Calcein, AM
中文别名:钙黄绿素乙酰氧基甲酯
英文别名:Calcein AM|Calcein-AM|148504-34-1|Glycine, N,N'-[[3',6'-bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-, 1,1'-bis[(acetyloxy)methyl] ester|acetyloxymethyl 2-[[2-(acetyloxy
纯度:≥96.0% (HPLC),用于荧光分析
货号:C131116
包装:1mg、5mg
Cas号:148504-34-1
存储温度:-20°C储存,充氩
产品介绍:
Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein , which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for Mdr (P-glycoprotein (Pgp) and multidrμg resistance protein (MRP)) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Studies sμggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition.A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule
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