Promethazine hydrochloride химические свойства, назначение, производство
Химические свойства
White Solid
Использование
Promethazine hydrochloride is used as antihistamine; antiemetic; central nervous system depressant; sedative; anticholinergic; antiserotoninergic; local anesthetic;
in the treatment of motion sickness, cough linctuses, nausea, and allergic conditions; used to control Parkinsonian symptoms and as
central nervous system depressant; in pills, syrup, injections and suppositories.
Определение
ChEBI: The hydrochloride salt of promethazine.
Общее описание
Odorless white to faint yellow crystalline powder. Bitter taste. A 10% solution in water has a pH of 3.5-5.0.
Реакции воздуха и воды
Slowly oxidizes in air, acquiring a blue color. Also turns blue on exposure to moisture. Water soluble.
Профиль реактивности
Promethazine hydrochloride is sensitive to light. In aqueous solution, Promethazine hydrochloride is degraded by heat and light (more rapidly in air or oxygen). Incompatible with alkalis and alkaline solutions such as those of aminophylline, soluble barbiturates and phenytoin sodium. Iron(III) and copper(III) accelerate the degradation .
Пожароопасность
Flash point data for Promethazine hydrochloride are not available; however, Promethazine hydrochloride is probably combustible.
Профиль безопасности
Poison by ingestion,
subcutaneous, intraperitoneal, and
intravenous routes. Human systemic effects
by ingestion: excitement, sleep, convulsions,
rigdity. Experimental teratogenic effects.
Other experimental reproductive effects.
When heated to decomposition it emits very
toxic fumes of HCl, SOx, and NOx. Used as
an antihstamine.
Promethazine hydrochloride препаратная продукция и сырье
сырьё
препарат