Аминогуанидин бикарбона
Аминогуанидин бикарбона атрибут
| Температура плавления: |
170-172 °C (dec.)(lit.) |
| плотность: |
1,6 g/cm3 |
| температура хранения: |
Store below +30°C. |
| растворимость: |
H2O: растворим 2,7 г/л при 20°C |
| форма: |
Кристаллический порошок |
| пка: |
6.19[at 20 ℃] |
| цвет: |
От белого до не совсем белого |
| РН: |
8.9 (5g/l, H2O, 20℃) |
| Растворимость в воде: |
<5 г/л (20 °C) |
| БРН: |
3569869 |
| ИнЧИКей: |
OTXHZHQQWQTQMW-UHFFFAOYSA-N |
| LogP: |
-6.61 at 25℃ |
| Справочник по базе данных CAS: |
2582-30-1(CAS DataBase Reference) |
| Рейтинг продуктов питания EWG: |
1-3 |
| FDA UNII: |
X2151435R9 |
| Система регистрации веществ EPA: |
Carbonic acid, compd. with hydrazinecarboximidamide (1:1) (2582-30-1) |
Аминогуанидин бикарбона химические свойства, назначение, производство
Химические свойства
White to off-white crystalline powder. It is almost insoluble in water, alcohol and other acids.
Использование
Aminoguanidine bicarbonate (AGB) is of practical importance because of its use in dyes, dispersants, explosives and other commercial applications. It is used in the synthesis of antitumor agents and antileukemic activity. Also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze.
прикладной
Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase). Aminoguanidine bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.
Биохимия/физиол Действия
Aminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage. Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.
Синтез
A synthesis method of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity aminoguanidine bicarbonate.
Аминогуанидин бикарбона препаратная продукция и сырье
сырьё
препарат
Митогуазон
7-BROMO-3-TRIFLUOROMETHYL-IMIDAZO[1,2-B][1,2,4]TRIAZINE
3-амино-1H-1,2,4-триазол
METOSULAM
Пимагедин
2- (2,3-дихлорфенил) -2-гуанидинилиминоацетонитрил
GUANABENZ ACETATE
5-METHYL-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-YLAMINE
1H-Pyrazole-1-carboximidamide,2,5-dihydro-4-(2-hydroxyethyl)-3-methyl-5-oxo-(9CI)
2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)
ОКСАЛИЛ МОНОГУАНИЛГИДРАЗИД
4H-Cyclopentapyrimidin-4-one, 2,3-diamino-3,5,6,7-tetrahydro- (9CI)
Аминогуанидин бикарбона поставщик
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